benzoic acid 2-oxo-1,2,2-triphenylethyl ester

Base Information

• Chemical Name: benzoic acid 2-oxo-1,2,2-triphenylethyl ester
• CAS No.: 73604-41-8
• Molecular Formula: C₂₇H₂₀O₃
• Molecular Weight: 392.454
• Mol file: 73604-41-8.mol

Synonyms:benzoic acid 2-oxo-1,2,2-triphenylethyl ester

Chemical Property of benzoic acid 2-oxo-1,2,2-triphenylethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoic acid 2-oxo-1,2,2-triphenylethyl ester

There total 8 articles about benzoic acid 2-oxo-1,2,2-triphenylethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 54.0%

α-benzoyldiphenylmethyl chloride (2510-77-2) + benzoic acid (65-85-0,8013-63-6) → benzoic acid 2-oxo-1,2,2-triphenylethyl ester (73604-41-8)

Guidance literature:

With silver tetrafluoroborate; silver carbonate; In dichloromethane; at -60 - 0 ℃;

DOI:10.1016/S0040-4039(03)00513-6

Reference yield: 0.28%

benzoyl chloride (98-88-4) + Dilithium benzophenone dianion (2036-66-0,15697-31-1) → 1,2,2-triphenylethenyl benzoate (5334-11-2) + benzoic acid 2-oxo-1,2,2-triphenylethyl ester (73604-41-8)

Guidance literature:

In tetrahydrofuran; for 0.5h;

DOI:10.1016/S0022-328X(00)83502-0

Reference yield:

α-phenylbenzoin (4237-46-1) → benzoic acid 2-oxo-1,2,2-triphenylethyl ester (73604-41-8)

Guidance literature:

Multi-step reaction with 2 steps

1: 64 percent / pyridine; thionyl chloride / 0 °C

2: 54 percent / silver(I) carbonate; silver(I) tetrafluoroborate / CH₂Cl₂ / -60 - 0 °C

With pyridine; silver tetrafluoroborate; thionyl chloride; silver carbonate; In dichloromethane;

DOI:10.1016/j.tet.2006.11.015

upstream raw materials:

2-bromo-1,2,2-triphenyl-ethanone

silver benzoate

2-methoxy-2,3,3-triphenyl-oxirane

benzoic acid

Refernces

• 1、 Ashraf, M. Arfan,Jones, Matthew A.,Kelly, Natalie E.,Mullaney, Alex,Snaith, John S.,Williams, Iwan. "Synthesis and photolysis studies of carboxylic esters of 2-hydroxy-1,2,2-triphenylethanone: A novel tandem photocyclisation". . p. 3151 - 3154. Retrieved 2007/10/03.