Technology Process of C23H20N6O3
There total 5 articles about C23H20N6O3 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
water; dimethyl sulfoxide;
at 20 ℃;
for 24h;
DOI:10.1016/j.bmcl.2014.03.026
- Guidance literature:
-
Multi-step reaction with 2 steps
1: methanol / 20 °C
2: tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; copper(II) sulfate; sodium L-ascorbate / dimethyl sulfoxide; water / 24 h / 20 °C
With
copper(II) sulfate; sodium L-ascorbate; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
methanol; water; dimethyl sulfoxide;
1: |Seyferth-Gilbert Homologation;
DOI:10.1016/j.bmcl.2014.03.026
- Guidance literature:
-
Multi-step reaction with 6 steps
1: thionyl chloride / dichloromethane / Reflux
2: triethylamine / dichloromethane / 20 °C
3: tris-(dibenzylideneacetone)dipalladium(0); XPhos; potassium carbonate / tert-butyl alcohol / Reflux
4: lithium aluminium tetrahydride / tetrahydrofuran / 0 °C
5: methanol / 20 °C
6: tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine; copper(II) sulfate; sodium L-ascorbate / dimethyl sulfoxide; water / 24 h / 20 °C
With
tris-(dibenzylideneacetone)dipalladium(0); lithium aluminium tetrahydride; thionyl chloride; potassium carbonate; copper(II) sulfate; sodium L-ascorbate; triethylamine; XPhos; tris[(1-benzyl-1H-1,2,3-triazol-4yl)methyl]amine;
In
tetrahydrofuran; methanol; dichloromethane; water; dimethyl sulfoxide; tert-butyl alcohol;
3: |Buchwald-Hartwig Coupling / 5: |Seyferth-Gilbert Homologation;
DOI:10.1016/j.bmcl.2014.03.026