2-benzoyl-4,5-dimethylimidazole

Base Information

• Chemical Name: 2-benzoyl-4,5-dimethylimidazole
• CAS No.: 853262-52-9
• Molecular Formula: C₁₂H₁₂N₂O
• Molecular Weight: 200.24
• Mol file: 853262-52-9.mol

Synonyms:2-benzoyl-4,5-dimethylimidazole

Chemical Property of 2-benzoyl-4,5-dimethylimidazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-benzoyl-4,5-dimethylimidazole

There total 5 articles about 2-benzoyl-4,5-dimethylimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C19H16N2O2 → 2-benzoyl-4,5-dimethylimidazole (853262-52-9)

Guidance literature:

With sodium hydroxide; In water; at 100 ℃; for 1h;

DOI:10.1016/j.ejmech.2018.05.051

Reference yield:

benzoyl chloride (98-88-4) → 2-benzoyl-4,5-dimethylimidazole (853262-52-9)

Guidance literature:

Multi-step reaction with 2 steps

1.1: pyridine; triethylamine / 0 °C

1.2: 3 h / 0 - 20 °C

2.1: sodium hydroxide / water / 1 h / 100 °C

With pyridine; triethylamine; sodium hydroxide; In water;

DOI:10.1016/j.ejmech.2018.05.051

Reference yield:

benzoic acid (65-85-0,8013-63-6) → 2-benzoyl-4,5-dimethylimidazole (853262-52-9)

Guidance literature:

Multi-step reaction with 3 steps

1.1: thionyl chloride / dichloromethane; N,N-dimethyl-formamide

2.1: pyridine; triethylamine / 0 °C

2.2: 3 h / 0 - 20 °C

3.1: sodium hydroxide / water / 1 h / 100 °C

With pyridine; thionyl chloride; triethylamine; sodium hydroxide; In dichloromethane; water; N,N-dimethyl-formamide;

DOI:10.1016/j.ejmech.2018.05.051

upstream raw materials:

benzoyl chloride

benzoic acid

4,5-dimethylimidazole

5-methyl-4-chloromethyl imidazole

Downstream raw materials:

2-benzoyl-1,3,4,5-tetramethylimidazolium iodide

Refernces