Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester

Base Information

• Chemical Name: Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester
• CAS No.: 612084-67-0
• Molecular Formula: C₂₈H₅₂O₄
• Molecular Weight: 452.718
• Mol file: 612084-67-0.mol

Synonyms:Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester

Chemical Property of Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester

There total 2 articles about Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 50.0%

(+)-(1S,2R,5S)-menthylchloroformate (7635-54-3,7635-53-2) + (S)-(S)-1-(Tetrahydro-furan-2-yl)-tridecan-1-ol → Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester (612084-67-0) + Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (S)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester

Guidance literature:

With pyridine; at 0 - 20 ℃; for 3.16667h;

Reference yield:

tridecanal (10486-19-8) → Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester (612084-67-0)

Guidance literature:

Multi-step reaction with 2 steps

1: triethylborane; tert-butyl hydroperoxide / various solvent(s) / 1 h / 20 °C

2: 50 percent / pyridine / 3.17 h / 0 - 20 °C

With pyridine; tert.-butylhydroperoxide; triethyl borane; In various solvent(s);

Reference yield: 61.0%

Carbonic acid (1S,2R,5S)-2-isopropyl-5-methyl-cyclohexyl ester (R)-(R)-1-(tetrahydro-furan-2-yl)-tridecyl ester (612084-67-0) → (+)-O-menthoxycarbonyl muricatacin (612084-71-6) + 4-keto-5-(menthoxycarbonyloxy)heptadecanoic acid

Guidance literature:

With ruthenium trichloride; sodium periodate; sodium hydrogencarbonate; In tetrachloromethane; water; acetonitrile; at 20 ℃;

upstream raw materials:

(+)-(1S,2R,5S)-menthylchloroformate

tridecanal

Downstream raw materials:

(+)-O-menthoxycarbonyl muricatacin

Refernces