(Heptafluoropropyl)trimethylsilane

Base Information

• Chemical Name: (Heptafluoropropyl)trimethylsilane
• CAS No.: 3834-42-2
• Molecular Formula: C6H9 F7 Si
• Molecular Weight: 242.212
• Hs Code.: 2931900090
• European Community (EC) Number: 624-436-1
• DSSTox Substance ID: DTXSID70400078
• Nikkaji Number: J1.503.676A
• Wikidata: Q81985921
• Mol file: 3834-42-2.mol

Synonyms:(Heptafluoropropyl)trimethylsilane;3834-42-2;Trimethyl(heptafluoropropyl)silane;1,1,2,2,3,3,3-heptafluoropropyl(trimethyl)silane;1-(Trimethylsilyl)heptafluoropropane;Silane,(1,1,2,2,3,3,3-heptafluoropropyl)trimethyl-;C6H9F7Si;SCHEMBL104119;Heptafluoropropyltrimethylsilane;Trimethyl(perfluoropropyl)silane;DTXSID70400078;PKLASFRWKXWKII-UHFFFAOYSA-N;MFCD00216712;AKOS015915752;(Heptafluoropropyl)trimethylsilane, 97%;BS-44162;T3593;T72406;J-500081;(1,1,2,2,3,3,3-Heptafluoropropyl)trimethyl-silane;(1,1,2,2,3,3,3-HEPTAFLUOROPROPYL)TRIMETHYLSILANE

Chemical Property of (Heptafluoropropyl)trimethylsilane

Chemical Property:

• Vapor Pressure: 105mmHg at 25°C
• Refractive Index: n20/D 1.324(lit.)
• Boiling Point: 88 °C(lit.)
• Flash Point: 20 °F
• PSA: 0.00000
• Density: 1.195 g/mL at 25 °C(lit.)
• LogP: 4.11660
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 2
• Exact Mass: 242.03617396
• Heavy Atom Count: 14
• Complexity: 211

Purity/Quality:

98%,99%, ^*data from raw suppliers

(Heptafluoropropyl)trimethylsilane ^*data from reagent suppliers

Safty Information:

• Statements: 10
• Safety Statements: 23-24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C[Si](C)(C)C(C(C(F)(F)F)(F)F)(F)F
• Uses: (Heptafluoropropyl)trimethylsilane is a reagent for nucleophilic perfluoroalkylation of organic and in organic substrates.

Technology Process of (Heptafluoropropyl)trimethylsilane

There total 4 articles about (Heptafluoropropyl)trimethylsilane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

chloro-trimethyl-silane (75-77-4) + 1,1,1,2,2,3,3-heptafluoro-3-iodo-propane (754-34-7) → (heptafluoropropyl)trimethylsilane (3834-42-2)

Guidance literature:

With Tetrakis(dimethylamino)ethylen; In diethylene glycol dimethyl ether; at -30 ℃; for 2h;

DOI:10.1016/S0040-4039(01)00447-6

Reference yield: 38.0%

1,1,1,2,2,3,3-heptafluoro-3-iodo-propane (754-34-7) + methyllithium (917-54-4) + dimethylsilicon dichloride (75-78-5,30107-43-8) → (heptafluoropropyl)trimethylsilane (3834-42-2) + dimethyl di(n-perfluoro propyl) silane (423-51-8)

Guidance literature:

In pentane; addition of CH3Li and n-C3F7I (formation of n-C3F7Li) to (CH3)2SiCl2 in pentane at -70°C (1 hour), heating to -40°C within 1 hour, cooling to -78°C, addition of CH3Li and heating to 27°C;;

Reference yield: 6.3%

chloro-trimethyl-silane (75-77-4) + 1,1,1,2,2,3,3-heptafluoro-3-iodo-propane (754-34-7) + methyllithium (917-54-4) → (heptafluoropropyl)trimethylsilane (3834-42-2)

Guidance literature:

In diethyl ether; addition of CH3Li and n-C3F7I (formation of n-C3F7Li) to (CH3)3SiCl in ether at -30°C, heating to -18°C within 45 minutes, -10°C (15 minutes), 6°C (45 minutes);;

upstream raw materials:

chloro-trimethyl-silane

heptafluoro-propyl lithium

1,1,1,2,2,3,3-heptafluoro-3-iodo-propane

methyllithium

Downstream raw materials:

1-nitro-4-(1,1,2,2,2-pentafluoroethyl)-benzene

1-(heptafluoropropyl)-1-cyclohexanol

1-phenyl-2,2,3,3,4,4,4-heptafluorobutan-1-ol

2-phenyl-3,3,4,4,5,5,5-heptafluoropentan-2-ol

Refernces

• 1、 Petrov, Viacheslav A.. "A simple procedure for nucleophilic perfluoroalkylation of organic and inorganic substrates". . p. 3267 - 3269. Retrieved 2007/10/03.