5-METHOXYBENZOFURAZAN 3-OXIDE

Base Information

• Chemical Name: 5-METHOXYBENZOFURAZAN 3-OXIDE
• CAS No.: 3524-06-9
• Molecular Formula: C7H6 N2 O3
• Molecular Weight: 166.136
• Hs Code.: 2934999090
• Mol file: 3524-06-9.mol

Synonyms:Benzofurazan,5-methoxy-, 3-oxide (6CI,7CI,8CI); 6-Methoxybenzofuroxan

Chemical Property of 5-METHOXYBENZOFURAZAN 3-OXIDE

Chemical Property:

• Vapor Pressure: 0.00344mmHg at 25°C
• Melting Point: 115-117 °C(lit.)
• Refractive Index: 1.628
• Boiling Point: 291.2°C at 760 mmHg
• Flash Point: 129.9°C
• PSA: 60.72000
• Density: 1.46g/cm³
• LogP: 1.26490

Purity/Quality:

5-METHOXYBENZOFURAZAN-3-OXIDE 99.00% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

Technology Process of 5-METHOXYBENZOFURAZAN 3-OXIDE

There total 2 articles about 5-METHOXYBENZOFURAZAN 3-OXIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

1-azido-4-methoxy-2-nitrobenzene (10336-13-7) → 6-methoxybenzofuroxan (3524-06-9) + 1-(4-Methoxy-2-nitro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester + 1-(4-Methoxy-2-nitro-phenyl)-1H-[1,2,3]triazole-4,5-dicarboxylic acid 4-ethyl ester + 1-(4-Methoxy-2-nitro-phenyl)-1H-[1,2,3]triazole-4,5-dicarboxylic acid diethyl ester (206976-25-2)

Guidance literature:

With sodium 1,4-diethoxy-1,4-dioxobut-2-en-2-olate; In ethanol; at 55 ℃; for 24h; Further byproducts given;

DOI:10.1016/S0223-5234(98)80036-6

Reference yield: 20.0%

1-azido-4-methoxy-2-nitrobenzene (10336-13-7) + diethyl oxalacetate sodium salt → 6-methoxybenzofuroxan (3524-06-9) + 1-(4-Methoxy-2-nitro-phenyl)-1H-[1,2,3]triazole-4-carboxylic acid ethyl ester + 1-(4-Methoxy-2-nitro-phenyl)-1H-[1,2,3]triazole-4,5-dicarboxylic acid 4-ethyl ester + 1-(4-Methoxy-2-nitro-phenyl)-1H-[1,2,3]triazole-4,5-dicarboxylic acid diethyl ester (206976-25-2)

Guidance literature:

In ethanol; at 55 ℃; for 24h; Further byproducts given;

DOI:10.1016/S0223-5234(98)80036-6

Reference yield: 91.0%

6-methoxybenzofuroxan (3524-06-9) + N-(but-3-en-1-yl)-4-methyl-N-(phenylethynyl)benzenesulfonamide (683246-91-5) → N-(4-methoxy-2-nitrophenyl)-1-phenyl-3-tosyl-3-azabicyclo-[3.1.0]hexan-2-imine

Guidance literature:

With [bis(trifluoromethanesulfonyl)imidate](triphenylphosphine)gold(I); In chlorobenzene; at 60 ℃; for 24h;

DOI:10.1021/acs.joc.1c01654

upstream raw materials:

1-azido-4-methoxy-2-nitrobenzene

Downstream raw materials:

4-methoxy-[1,2]benzoquinone dioxime

(7-methoxy-3-methyl-1,4-dioxy-quinoxalin-2-yl)-phenyl-methanone

Refernces