Azane;2-hydroxyacetic acid

Base Information

• Chemical Name: Azane;2-hydroxyacetic acid
• CAS No.: 35249-89-9
• Molecular Formula: C2H4 O3 . H3 N
• Molecular Weight: 93.0825
• Wikidata: Q27270361
• Mol file: 35249-89-9.mol

Synonyms:UBKBVPONTPMQQW-UHFFFAOYSA-N;Q27270361

Chemical Property of Azane;2-hydroxyacetic acid

Chemical Property:

• Vapor Pressure: 0.00125mmHg at 25°C
• Boiling Point: 265.6°C at 760 mmHg
• Flash Point: 128.7°C
• PSA: 60.36000
• Density: 0.99 at 20℃
• LogP: -1.89520
• Hydrogen Bond Donor Count: 3
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 93.042593085
• Heavy Atom Count: 6
• Complexity: 40.2

Purity/Quality:

99.9% ^*data from raw suppliers

AMMONIUMGLYCOLATE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C(C(=O)O)O.N

Technology Process of Azane;2-hydroxyacetic acid

There total 9 articles about Azane;2-hydroxyacetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

glycolonitrile (107-16-4) → glycolic acid ammonium salt (35249-89-9)

Guidance literature:

With ammonium hydroxide; immobilized E_. coli MG₁₆₅₅/pSW₁₃₈-Phe₁₆₈Val nitrilaze; at 25 ℃; pH=7.0 - 7.5;

DOI:10.1002/adsc.200700061

Reference yield:

ammonia (7664-41-7) + sodium (7440-23-5) → ammonium glycolate (35249-89-9) + diammonium rhodizonate + glycolamide (598-42-5) + sodium glycolate (25289-18-3,105938-46-3,2836-32-0) + sodium rhodizonate dibasic (523-21-7)

Guidance literature:

With carbon monoxide; ammonium chloride; In ammonia; adding NH4Cl before evapn. of NH3;

Reference yield:

1,3-dihydroxyacetone dimer (62147-49-3) → ammonium formate (16712-16-6,64165-14-6,65387-22-6,70179-79-2,540-69-2) + glycolic acid ammonium salt (35249-89-9)

Guidance literature:

With ammonium hydroxide; dihydrogen peroxide; In water; at 20 ℃; for 1h;

DOI:10.1016/j.tetlet.2010.09.092

upstream raw materials:

glycolonitrile

glycolic Acid

1,3-dihydroxyacetone dimer

D-Fructose

Downstream raw materials:

trimethylsilyl [(trimethylsilyl)oxy]acetate

glycolic Acid

glycolamide

glycolic acid methyl ester

Refernces

• 1、 Panova, Anna,Mersinger, Lawrence J.,Liu, Qiang,Foo, Thomas,Roe, D. Christopher,Spillan, William L.,Sigmund, Amy E.,Ben-Bassat, Arie,Winona Wagner,O'Keefe, Daniel P.,Wu, Shijun,Perrillo, Kelly L.,Payne, Mark S.,Breske, Stephen T.,Gallagher, F. Glenn,Dicosimo, Robert. "Chemoenzymatic synthesis of glycolic acid". . p. 1462 - 1474. Retrieved 2008/03/28.
• 2、 -. "Process for slurry fischer-tropsch hydrocarbon synthesis with high surface area reduced-carbided iron/manganese catalysts". . . Retrieved 2008/06/13.