β-morpholinyl-N,N-morpholinylpropionic acid amide

Base Information

• Chemical Name: β-morpholinyl-N,N-morpholinylpropionic acid amide
• CAS No.: 3773-84-0
• Molecular Formula: C₁₁H₂₀N₂O₃
• Molecular Weight: 228.291
• Mol file: 3773-84-0.mol

Synonyms:β-morpholinyl-N,N-morpholinylpropionic acid amide

Chemical Property of β-morpholinyl-N,N-morpholinylpropionic acid amide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of β-morpholinyl-N,N-morpholinylpropionic acid amide

There total 1 articles about β-morpholinyl-N,N-morpholinylpropionic acid amide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + acryloyl chloride (814-68-6,25189-84-8) → N-Acryloylmorpholine (5117-12-4,28902-82-1) + β-morpholinyl-N,N-morpholinylpropionic acid amide (3773-84-0)

Guidance literature:

With triethylamine; benzene;

DOI:10.1002/pol.1958.1202912008

Reference yield: 95.0%

β-morpholinyl-N,N-morpholinylpropionic acid amide (3773-84-0) + acetic anhydride (108-24-7) → 4-acetylmorpholine (1696-20-4) + N-Acryloylmorpholine (5117-12-4,28902-82-1)

Guidance literature:

β-morpholinyl-N,N-morpholinylpropionic acid amide; acetic anhydride; In toluene; at 20 - 80 ℃; for 2h; Inert atmosphere;

With 2,6-di-tert-butyl-4-methyl-phenol; N-ethyl-N,N-diisopropylamine; for 18h; Reagent/catalyst; Temperature; Reflux;

Reference yield: 89.0%

β-morpholinyl-N,N-morpholinylpropionic acid amide (3773-84-0) → N-Acryloylmorpholine (5117-12-4,28902-82-1)

Guidance literature:

With 10H-phenothiazine; copper(II) bis(trifluoromethanesulfonate); at 135 ℃; for 2h; Inert atmosphere;

upstream raw materials:

morpholine

acryloyl chloride

Downstream raw materials:

N-Acryloylmorpholine

4-benzyl-morpholine

4-acetylmorpholine

2-methyl-1-morpholinoprop-2-en-1-one