2-(2-formylphenyl)benzoic Acid

Base Information

• Chemical Name: 2-(2-formylphenyl)benzoic Acid
• CAS No.: 6720-26-9
• Molecular Formula: C14H10O3
• Molecular Weight: 226.232
• Hs Code.: 2918300090
• European Community (EC) Number: 804-042-8
• DSSTox Substance ID: DTXSID90383354
• Nikkaji Number: J1.585.413H
• Wikidata: Q82175029
• Mol file: 6720-26-9.mol

Synonyms:2-(2-formylphenyl)benzoic Acid;6720-26-9;2'-formylbiphenyl-2-carboxylic acid;2'-formyl-[1,1'-biphenyl]-2-carboxylic acid;2'-formyl[1,1'-biphenyl]-2-carboxylic acid;2'-Formyl-biphenyl-2-carboxylic acid;[1,1'-Biphenyl]-2-carboxylicacid, 2'-formyl-;2'-Formyl-2-biphenylcarboxylic acid;SCHEMBL547698;DTXSID90383354;2-formyl-2'-biphenylcarboxylic acid;BBL000534;MFCD04039066;STK796833;AKOS004114024;AB92575;NCGC00327480-01;VS-00638;BB 0220638;CS-0374109;FT-0726925;2'-formyl-[1,1'-biphenyl]-2-carboxylicacid;EN300-396837;F79744;AB01322499-02;2-FORMYL[1,1-BIPHENYL]-2-CARBOXYLICACID;A814726;Z2587943009;2'-Formyl[1,1'-biphenyl]-2-carboxylic acid, AldrichCPR

Chemical Property of 2-(2-formylphenyl)benzoic Acid

Chemical Property:

• Melting Point: 128 °C
• Boiling Point: 413.2 °C at 760 mmHg
• Flash Point: 217.9 °C
• PSA: 54.37000
• Density: 1.264 g/cm³
• LogP: 2.86430
• XLogP3: 2
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 226.062994177
• Heavy Atom Count: 17
• Complexity: 287

Purity/Quality:

98%Min ^*data from raw suppliers

2-(2-Formylphenyl)benzoicacid ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi,Xn
• Statements: 22-36/37/38-51
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C(=C1)C=O)C2=CC=CC=C2C(=O)O

Technology Process of 2-(2-formylphenyl)benzoic Acid

There total 3 articles about 2-(2-formylphenyl)benzoic Acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 20.0%

hydrogen cyanide (74-90-8) + diphenic-mercuric acid anhydride (84216-46-6) → 2-(2-formyl-phenyl)-benzoic acid (6720-26-9) + 2-Biphenylcarboxylic acid (947-84-2)

Guidance literature:

In acetic acid; for 50h;

Reference yield:

phenanthrene (85-01-8) → 2-Phenylbenzaldehyde (1203-68-5) + naphthalene-1,2-dicarboxylic acid (2088-87-1) + 2-(2-formyl-phenyl)-benzoic acid (6720-26-9) + benzene-1,2-dicarboxylic acid (88-99-3,73607-73-5)

Guidance literature:

With air; silica gel; for 65h; Further byproducts given; Photolysis;

DOI:10.1021/es950769p

Reference yield:

phenanthrene (85-01-8) → 2-(2-formyl-phenyl)-benzoic acid (6720-26-9) + Biphenyl-2,2'-dicarbaldehyde (1210-05-5)

Guidance literature:

With dimethylsulfide; ozone; Yield given. Multistep reaction. Yields of byproduct given; 1.) CH₂Cl₂, -78 deg C, 2.) CH₂Cl₂, RT, 72 h;

DOI:10.1080/00397919308011249

upstream raw materials:

hydrogen cyanide

diphenic-mercuric acid anhydride

phenanthrene

Downstream raw materials:

2'-<1,1-(ethylenedioxy)-2-propen-1-yl>biphenyl-2-carboxylic acid

2'-<1,1-(ethylenedioxy)propyl>biphenyl-2-carboxylic acid

Te-4-fluorophenyl 2'-<1,1-(ethylenedioxy)-2-propen-1-yl>biphenyl-2-tellurocarboxylate

N-benzyl-6-isobutyl-7-oxo-6,7-dihydro-5H-dibenzo[c,e]azepine-5-carboxamide

Refernces

• 1、 Hon, Yung-Son,Lin, Sheng-Wun,Lu, Ling,Chen, Yao-Jung. "The mechanistic study and synthetic applications of the base treatment in the ozonolytic reactions". . p. 5019 - 5034. Retrieved 2007/10/02.
• 2、 Takahashi, Teruo,Togashi, Shigeo,Morishita, Muneo,Takeda, Shiro. "Syntheses of Diphenic Anhydride-Mercury Compounds and Their Reaction with Nucleophilic Reagents". . p. 3020 - 3023. Retrieved 2007/10/02.