N,N,N',N'-TETRAETHYLMALONAMIDE

Base Information

• Chemical Name: N,N,N',N'-TETRAETHYLMALONAMIDE
• CAS No.: 33931-42-9
• Molecular Formula: C11H22 N2 O2
• Molecular Weight: 214.308
• Hs Code.: 2924199090
• Mol file: 33931-42-9.mol

Synonyms:Malonamide,N,N,N',N'-tetraethyl- (8CI); Propanediamide, N,N,N',N'-tetraethyl- (9CI);N,N,N',N'-Tetraethyl-1,3-propanediamide; N,N,N',N'-Tetraethylmalonamide

Chemical Property of N,N,N',N'-TETRAETHYLMALONAMIDE

Chemical Property:

• Refractive Index: 1.4740 to 1.4790
• Boiling Point: 162 °C / 10mmHg
• Flash Point: 133.3oC
• PSA: 40.62000
• Density: 0.979g/cm3
• LogP: 1.11330

Purity/Quality:

98%,99%, ^*data from raw suppliers

N,N,N',N'-Tetraethylmalonamide >97.0%(GC) ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N,N',N'-TETRAETHYLMALONAMIDE

There total 3 articles about N,N,N',N'-TETRAETHYLMALONAMIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

carbon monoxide (201230-82-2) + diethylamine (109-89-7) + 1,1-dibromomethane (74-95-3) → diethylacetamide (685-91-6) + N,N-diethyl-2-diethylaminoacetamide (27794-54-3) + N,N,N',N'-tetraethylmalonamide (33931-42-9)

Guidance literature:

With triethylamine; dicobalt octacarbonyl; In hexane; at 100 ℃; for 48h; under 38000 Torr; Yield given. Yields of byproduct given; K₂CO₃, other solvents;

DOI:10.1016/S0040-4039(00)74885-4

Reference yield:

dichloromethane (75-09-2) + carbon monoxide (201230-82-2) + diethylamine (109-89-7) → diethylacetamide (685-91-6) + N,N-diethyl-2-diethylaminoacetamide (27794-54-3) + N,N,N',N'-tetraethylmalonamide (33931-42-9)

Guidance literature:

With potassium carbonate; dicobalt octacarbonyl; at 100 ℃; for 48h; under 38000 Torr; Yield given. Yields of byproduct given;

DOI:10.1016/S0040-4039(00)74885-4

Reference yield:

N,N,N',N'-tetraetil-2-<(2-nitrofenil)tio>malonammide (117378-63-9) → N,N,N',N'-tetraethylmalonamide (33931-42-9) + 2-<(2-amminofenil)tio>-N,N,N',N'-tetraetilmalonammide (117378-54-8)

Guidance literature:

With hydrogen; palladium on activated charcoal; In tetrahydrofuran; under 2280 Torr; Ambient temperature;

upstream raw materials:

N,N,N',N'-tetraetil-2-<(2-nitrofenil)tio>malonammide

dichloromethane

carbon monoxide

diethylamine

Downstream raw materials:

2-(N-Diethylcarbamoyl)-3-oxo-2,3-dihydro-benzoxazin-1,4

2-(4-cloro-5-metil-2-nitrofenossi)-N,N,N',N'-tetraetilmalonammide

2-(2-ammino-4-cloro-5-metilfenossi)-N,N,N',N'-tetraetilmalonammide

3-(dietylamino)-N,N-diethyl-2H-pyrido<3,2-b><1,4>oxazine-2-carboxamide

Refernces

• 1、 Balbi, A.,Ferreccio, R.,Braccio, M. Di,Mazzei, M.,Roma, G.. "2H-1,4-BENZOTIAZINE 3-(DIALCHILAMMINO)SOSTITUITE". . p. 955 - 962. Retrieved 2007/10/02.