Technology Process of N-benzylclavulanamide
There total 5 articles about N-benzylclavulanamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
sodium hydroxide; dicyclohexyl-carbodiimide;
In
tetrahydrofuran; dichloromethane; ethyl acetate;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: 70 percent / sodium hydroxide / H2O / 1.17 h / 0 °C
2: 69 percent / dimethylformamide / 1.5 h / Ambient temperature
3: 84 percent / H2 / palladium on carbon / ethanol / 0.75 h / 760 Torr / Ambient temperature
4: 67 percent / 1.0 M sodium hydroxide, pH=7, dicyclohexylcarbodi-imide / ethyl acetate; CH2Cl2; tetrahydrofuran
With
sodium hydroxide; hydrogen; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane; water; ethyl acetate; N,N-dimethyl-formamide;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 69 percent / dimethylformamide / 1.5 h / Ambient temperature
2: 84 percent / H2 / palladium on carbon / ethanol / 0.75 h / 760 Torr / Ambient temperature
3: 67 percent / 1.0 M sodium hydroxide, pH=7, dicyclohexylcarbodi-imide / ethyl acetate; CH2Cl2; tetrahydrofuran
With
sodium hydroxide; hydrogen; dicyclohexyl-carbodiimide;
palladium on activated charcoal;
In
tetrahydrofuran; ethanol; dichloromethane; ethyl acetate; N,N-dimethyl-formamide;