2-N-Cyclopropylamino-4,6-DichloroTriazine

Base Information

• Chemical Name: 2-N-Cyclopropylamino-4,6-DichloroTriazine
• CAS No.: 32889-45-5
• Molecular Formula: C6H6 Cl2 N4
• Molecular Weight: 205.046
• Hs Code.: 2933699090
• Mol file: 32889-45-5.mol

Synonyms:s-Triazine,2,4-dichloro-6-(cyclopropylamino)- (8CI);2,4-Dichloro-6-cyclopropylamino-1,3,5-triazine; 2-Cyclopropylamino-4,6-dichloro-s-triazine

Chemical Property of 2-N-Cyclopropylamino-4,6-DichloroTriazine

Chemical Property:

• Boiling Point: 401.8±28.0 °C(Predicted)
• PKA: 0.96±0.10(Predicted)
• PSA: 50.70000
• Density: 1.684±0.06 g/cm3(Predicted)
• LogP: 1.82570
• Storage Temp.: under inert gas (nitrogen or Argon) at 2–8 °C

Purity/Quality:

≥95% ^*data from raw suppliers

4,6-dichloro-N-cyclopropyl-1,3,5-triazin-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-N-Cyclopropylamino-4,6-DichloroTriazine

There total 2 articles about 2-N-Cyclopropylamino-4,6-DichloroTriazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1,3,5-trichloro-2,4,6-triazine (108-77-0) + Cyclopropylamine (765-30-0) → 2,4-dichloro-6-cyclopropylamino-1,3,5-triazine (32889-45-5)

Guidance literature:

1,3,5-trichloro-2,4,6-triazine; Cyclopropylamine; In chlorobenzene; at -10 ℃; for 0.5h; Inert atmosphere;

With sodium hydroxide; In chlorobenzene; at -10 - 20 ℃; for 16.5h; Inert atmosphere;

DOI:10.3109/14756366.2012.755622

Reference yield:

→ 2,4-dichloro-6-cyclopropylamino-1,3,5-triazine (32889-45-5)

Guidance literature:

Reference yield: 93.5%

2,4-dichloro-6-cyclopropylamino-1,3,5-triazine (32889-45-5) → cyromazine (66215-27-8)

Guidance literature:

With ammonia; In water; toluene; at 120 ℃; for 10h; under 4500.45 Torr;

upstream raw materials:

1,3,5-trichloro-2,4,6-triazine

Cyclopropylamine

Downstream raw materials:

6-chloro-N-cyclopropyl-[1,3,5]triazine-2,4-diamine

cyromazine

Refernces

• 1、 Modh, Rahul P.,De Clercq, Erik,Pannecouque, Christophe,Chikhalia, Kishor H.. "Design, synthesis, antimicrobial activity and anti-HIV activity evaluation of novel hybrid quinazoline-triazine derivatives". . p. 100 - 108. Retrieved 2014/03/21.
• 2、 -. "Selective NPY (Y5) antagonists (triazines)". Page column 17. . Retrieved 2010/01/30.