1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene

Base Information

• Chemical Name: 1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene
• CAS No.: 336-34-5
• Molecular Formula: C6H3 Cl F6 O
• Molecular Weight: 240.533
• Hs Code.: 2909209000
• European Community (EC) Number: 621-878-7
• DSSTox Substance ID: DTXSID80401197
• Wikidata: Q82204252
• Mol file: 336-34-5.mol

Synonyms:1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene;336-34-5;SCHEMBL11744184;DTXSID80401197;QLPINEFCFXPUSF-UHFFFAOYSA-N;1-CHLORO-3,3,4,4,5,5-HEXAFLUORO-2-METHOXYCYCLOPENT-1-ENE;MFCD00674036;AKOS015912741;1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene, 97%;Ether, 2-chloro-3,3,4,4,5,5-hexafluoro-1-cyclopenten-1-yl methyl

Chemical Property of 1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene

Chemical Property:

• Vapor Pressure: 9.61E-08mmHg at 25°C
• Refractive Index: n20/D 1.376(lit.)
• Boiling Point: 84 °C(lit.)
• Flash Point: 49 °C
• PSA: 9.23000
• Density: 1.56 g/mL at 25 °C(lit.)
• LogP: 3.00270
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 7
• Rotatable Bond Count: 1
• Exact Mass: 239.9776614
• Heavy Atom Count: 14
• Complexity: 297

Purity/Quality:

98%,99%, ^*data from raw suppliers

1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene 97% ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi
• Statements: 10-36/37/38
• Safety Statements: 16-26-36

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=C(C(C(C1(F)F)(F)F)(F)F)Cl
• Uses: Used in the preparation of perhalocyclopentanones and more recently to prepare tetracarbocyanine dyes with fluorinated rings in the side chain.

Technology Process of 1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene

There total 4 articles about 1-Chloro-3,3,4,4,5,5-hexafluoro-2-methoxycyclopentene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1,2-dichloro-3,3,4,4,5,5-hexafluorocyclopentene (706-79-6) → 1-chloro-3,3,4,4,5,5-hexafluoro-2-methoxy-cyclopentene (336-34-5)

Guidance literature:

With potassium hydroxide;

Reference yield:

methanol (67-56-1) + 1,2-dichloro-3,3,4,4,5,5-hexafluorocyclopentene (706-79-6) → 1-chloro-3,3,4,4,5,5-hexafluoro-2-methoxy-cyclopentene (336-34-5)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/jo01271a017 DOI:10.1039/j39690002329

Reference yield:

methanol (67-56-1) + 1,2,2,3,3,4,4-heptafluoro-5-chlorocyclopentene (1759-63-3) → 1-chloro-3,3,4,4,5,5-hexafluoro-2-methoxy-cyclopentene (336-34-5)

Guidance literature:

With potassium hydroxide;

DOI:10.1021/jo01344a056

upstream raw materials:

1,2-dichloro-3,3,4,4,5,5-hexafluorocyclopentene

methanol

1,2,2,3,3,4,4-heptafluoro-5-chlorocyclopentene

Downstream raw materials:

perfluorocyclopentanone

hexafluoroglutaric acid