m-methyl-N,N-dimethylaniline-N-oxide

Base Information

• Chemical Name: m-methyl-N,N-dimethylaniline-N-oxide
• CAS No.: 825-80-9
• Molecular Formula: C₉H₁₃NO
• Molecular Weight: 151.208
• Mol file: 825-80-9.mol

Synonyms:m-methyl-N,N-dimethylaniline-N-oxide

Chemical Property of m-methyl-N,N-dimethylaniline-N-oxide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of m-methyl-N,N-dimethylaniline-N-oxide

There total 1 articles about m-methyl-N,N-dimethylaniline-N-oxide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

N,N-dimethyl-m-toluidine (121-72-2) → m-methyl-N,N-dimethylaniline-N-oxide (825-80-9)

Guidance literature:

With dihydrogen peroxide; In acetonitrile; at 80 ℃; for 4.5h; under 760.051 Torr;

DOI:10.1039/c3cy00963g

Reference yield: 76.0%

m-methyl-N,N-dimethylaniline-N-oxide (825-80-9) + ethyl acrylate (140-88-5,9003-32-1) → (E)-ethyl 3-(2-(dimethylamino)-4-methylphenyl)acrylate

Guidance literature:

With silver hexafluoroantimonate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; 2,2-dimethyl-propanol-1; C₅H₁₁O^(1-)*Cs⁽¹⁺⁾; In methanol; at 20 ℃; for 24h; regioselective reaction; Schlenk technique; Inert atmosphere;

DOI:10.1002/anie.201307174

Reference yield: 73.0%

m-methyl-N,N-dimethylaniline-N-oxide (825-80-9) + diphenyl acetylene (501-65-5) → 1,6-dimethyl-2,3-diphenyl-1H-indole (1610871-11-8)

Guidance literature:

With silver tetrafluoroborate; dichloro(pentamethylcyclopentadienyl)rhodium (III) dimer; mesitylenecarboxylic acid; In tert-butyl alcohol; at 115 ℃; for 10h; regioselective reaction;

DOI:10.1021/acscatal.6b00311

upstream raw materials:

N,N-dimethyl-m-toluidine

Downstream raw materials:

2-(N,N-dimethylamino)-6-methylphenol

2-(N,N-dimethylamino)-4-methylphenol

2-(N,N-dimethylamino)-4-methylphenyl trifluoromethanesulfonate

2-(N,N-dimethylamino)-6-methylphenyl trifluoromethanesulfonate

Refernces

• 1、 Gopiraman, Mayakrishnan,Bang, Hyunsik,Babu, Sundaram Ganesh,Wei, Kai,Karvembu, Ramasamy,Kim, Ick Soo. "Catalytic N-oxidation of tertiary amines on RuO2NPs anchored graphene nanoplatelets". . p. 2099 - 2106. Retrieved 2014/06/24.