Isonicotinicacidpotassiumsalt

Base Information

• Chemical Name: Isonicotinicacidpotassiumsalt
• CAS No.: 25108-37-6
• Molecular Formula: C6H5 N O2 . K
• Molecular Weight: 161.202
• Hs Code.: 2933399090
• Mol file: 25108-37-6.mol

Synonyms:4-Pyridinecarboxylicacid, potassium salt (9CI); Isonicotinic acid, potassium salt (8CI); Potassium4-nicotinate; Potassium 4-pyridinecarboxylate; Potassium isonicotinate

Chemical Property of Isonicotinicacidpotassiumsalt

Chemical Property:

• PSA: 53.02000
• LogP: -0.55490

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Isonicotinicacidpotassiumsalt

There total 2 articles about Isonicotinicacidpotassiumsalt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

pyridine-4-methanol (586-95-8) → potassium pyridine-4-carboxylate (25108-37-6)

Guidance literature:

With C₁₅H₂₇Br₂CoN₃; potassium hydroxide; In toluene; at 140 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.orglett.0c00193

Reference yield:

pyridine-4-carboxylic acid (55-22-1) → potassium pyridine-4-carboxylate (25108-37-6)

Guidance literature:

With potassium hydroxide; In water; at 20 ℃; for 0.5h;

DOI:10.1515/chempap-2015-0042

Reference yield: 92.0%

pyridine-4-carboxylic acid (55-22-1) + potassium pyridine-4-carboxylate (25108-37-6) → isonicotinic anhydride (7082-71-5)

Guidance literature:

pyridine-4-carboxylic acid; With trichloroisocyanuric acid; triphenylphosphine; In dichloromethane; at 0 - 20 ℃;

potassium pyridine-4-carboxylate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1515/chempap-2015-0042

upstream raw materials:

pyridine-4-carboxylic acid

pyridine-4-methanol

Downstream raw materials:

4-pyridinecarboxylic acid, methyl ester

isonicotinic acid ethylester

benzyl 4-pyridinecarboxylate

piroximone

Refernces

• 1、 Rouhi-Saadabad, Hamed,Akhlaghinia, Batool. "Facile and direct synthesis of symmetrical acid anhydrides using a newly prepared powerful and efficient mixed reagent". . p. 479 - 485. Retrieved 2015/01/30.