METHYL 10-UNDECYNOATE

Base Information

• Chemical Name: METHYL 10-UNDECYNOATE
• CAS No.: 2777-66-4
• Molecular Formula: C12H20O2
• Molecular Weight: 196.29
• Hs Code.: 2916190090
• Mol file: 2777-66-4.mol

Synonyms:Methyl10-undecynoate;

Chemical Property of METHYL 10-UNDECYNOATE

Chemical Property:

• Vapor Pressure: 0.02mmHg at 25°C
• Melting Point: 42°C
• Refractive Index: 1.447
• Boiling Point: 251.9 °C at 760 mmHg
• Flash Point: 98.4 °C
• PSA: 26.30000
• Density: 0.917 g/cm³
• LogP: 2.91340

Purity/Quality:

98%min ^*data from raw suppliers

METHYL10-UNDECYNOATE,98% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Uses: Methyl 10-Undecynoate is a chemical reagent which undergoes hydrosilylation catalyzed by ruthenium cationic acetonitrile cyclopentadienyl half-sandwich complexes to give α-substituted vinylsilanes.

Technology Process of METHYL 10-UNDECYNOATE

There total 13 articles about METHYL 10-UNDECYNOATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methanol (67-56-1) + undec-10-ynoic acid (2777-65-3) → methyl 10-undecynoate (2777-66-4)

Guidance literature:

With toluene-4-sulfonic acid; for 17h; Reflux;

DOI:10.1021/acs.joc.7b03223

Reference yield: 50.0%

diphenylmethylsilanecarboxylic acid (18414-58-9) + sodium methylate (124-41-4) + 10-iododec-1-yne → methyl 10-undecynoate (2777-66-4)

Guidance literature:

With potassium fluoride; propyl cyanide; (4s,6s)-2,4,5,6-tetra(9H-carbazol-9-yl)isophthalonitrile; (2-morpholino-N-(quinolin-8-yl)acetamido)nickel(II) chloride; triethylamine; In N,N-dimethyl-formamide; at 20 ℃; for 20h; Inert atmosphere; Sealed tube; Irradiation;

DOI:10.1021/jacs.1c09170

Reference yield:

methanol (67-56-1) + chloro-trimethyl-silane (75-77-4) + undec-10-ynoic acid (2777-65-3) → methyl 10-undecynoate (2777-66-4)

Guidance literature:

at 20 ℃; for 12h;

upstream raw materials:

methanol

undec-10-ynoic acid

undeca-10-ynoic acid chloride

Methyl 10-undecenoate

Downstream raw materials:

1,1-diphenyl-undec-10-yn-1-ol

undec-10-yn-1-ol

undec-10-ynoic acid

10-Undecen-1-ol

Refernces

• 1、 Birepinte, Mélodie,Champagne, Pier Alexandre,Paquin, Jean-Fran?ois. "Photoinitiated anti-Hydropentafluorosulfanylation of Terminal Alkynes". supporting information. . Retrieved 2021/11/30.
• 2、 -. "IMMUNOTHERAPEUTIC AGENT". Paragraph 0101-0102. . Retrieved 2018/07/29.