5-phenyl-3,4-dihydro-2H-pyrrole perchlorate

Base Information

• Chemical Name: 5-phenyl-3,4-dihydro-2H-pyrrole perchlorate
• CAS No.: 69105-60-8
• Molecular Formula: C₁₀H₁₁N*ClHO₄
• Molecular Weight: 245.663
• Mol file: 69105-60-8.mol

Synonyms:5-phenyl-3,4-dihydro-2H-pyrrole perchlorate

Chemical Property of 5-phenyl-3,4-dihydro-2H-pyrrole perchlorate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-phenyl-3,4-dihydro-2H-pyrrole perchlorate

There total 4 articles about 5-phenyl-3,4-dihydro-2H-pyrrole perchlorate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-phenyl-1-pyrroline (700-91-4) → 5-phenyl-3,4-dihydro-2H-pyrrole perchlorate (69105-60-8)

Guidance literature:

With perchloric acid; In methanol; for 0.5h;

DOI:10.1016/j.bmc.2020.115547

Reference yield:

3-benzoyl-N-vinylpyrrolidin-2-one (125330-80-5) → 5-phenyl-3,4-dihydro-2H-pyrrole perchlorate (69105-60-8)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / tetrahydrofuran; water / 6 h / Reflux

2: perchloric acid / methanol / 0.5 h

With hydrogenchloride; perchloric acid; In tetrahydrofuran; methanol; water;

DOI:10.1016/j.bmc.2020.115547

Reference yield:

benzoic acid ethyl ester (93-89-0,99341-95-4) → 5-phenyl-3,4-dihydro-2H-pyrrole perchlorate (69105-60-8)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydride / tetrahydrofuran / 10 h / Reflux

2: hydrogenchloride / tetrahydrofuran; water / 6 h / Reflux

3: perchloric acid / methanol / 0.5 h

With hydrogenchloride; perchloric acid; sodium hydride; In tetrahydrofuran; methanol; water;

DOI:10.1016/j.bmc.2020.115547

upstream raw materials:

benzoic acid ethyl ester

3-benzoyl-N-vinylpyrrolidin-2-one

2-phenyl-1-pyrroline

Downstream raw materials:

2-phenyl-2-(tetrahydrofuran-2-yl)pyrrolidine

2-(3'-methyl-1',2'-butadien-1'-yl)-2-phenylpyrrolidine

2-(2'-methyl-3'-butyn-2'-yl)-2-phenylpyrrolidine

2-(2'-methoxy-3'-methyl-2'-butenyl)-2-phenylpyrrolidine

Refernces