Technology Process of (Z)-methyl 2-(methoxymethylene)-8-phenyl-3-vinyloctanoate
There total 10 articles about (Z)-methyl 2-(methoxymethylene)-8-phenyl-3-vinyloctanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
Ph3PAuSbF6;
In
nitromethane;
at -15 ℃;
for 20h;
chemoselective reaction;
DOI:10.1021/ol4001087
- Guidance literature:
-
Multi-step reaction with 5 steps
1: pyridinium chlorochromate; sodium acetate; sodium hydrogencarbonate / dichloromethane / 12 h / 20 °C
2: dichloromethane / 2 h / 20 °C
3: diisobutylaluminium hydride / tetrahydrofuran / 3 h / 0 - 20 °C
4: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 °C
5: Ph3PAuSbF6 / nitromethane
With
Ph3PAuSbF6; sodium acetate; sodium hydride; diisobutylaluminium hydride; sodium hydrogencarbonate; pyridinium chlorochromate;
In
tetrahydrofuran; nitromethane; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/ol4001087
- Guidance literature:
-
Multi-step reaction with 4 steps
1: dichloromethane / 2 h / 20 °C
2: diisobutylaluminium hydride / tetrahydrofuran / 3 h / 0 - 20 °C
3: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 20 °C
4: Ph3PAuSbF6 / nitromethane
With
Ph3PAuSbF6; sodium hydride; diisobutylaluminium hydride;
In
tetrahydrofuran; nitromethane; dichloromethane; N,N-dimethyl-formamide; mineral oil;
DOI:10.1021/ol4001087
