6-phenylhexanal

Base Information

• Chemical Name: 6-phenylhexanal
• CAS No.: 16387-61-4
• Molecular Formula: C12H16O
• Molecular Weight: 176.258
• Mol file: 16387-61-4.mol

Synonyms:16-Oxo-1-n-hexyl-benzol;6-Phenyl-hexan-3-on;ethyl 3-phenylpropyl ketone;6-phenyl-3-hexanone;1-Phenyl-hexanon-(4);6-phenyl-hexanal;6-phenyl-hexan-3-one;3-Hexanone,6-phenyl;

Chemical Property of 6-phenylhexanal

Chemical Property:

• Vapor Pressure: 0.003mmHg at 25°C
• Boiling Point: 283.744oC at 760 mmHg
• Flash Point: 138.1oC
• PSA: 17.07000
• Density: 0.95g/cm3
• LogP: 2.98840

Purity/Quality:

99% ^*data from raw suppliers

Benzenehexanal ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 6-phenylhexanal

There total 18 articles about 6-phenylhexanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

6-phenyl-1-hexanol (2430-16-2) → 6-phenylhexanal (16387-61-4)

Guidance literature:

With oxalyl dichloride; triethylamine; In dichloromethane; dimethyl sulfoxide; at -78 ℃;

DOI:10.1002/anie.201306295

Reference yield: 94.0%

6-phenyl-hexanoic acid methyl ester (5581-76-0) → 6-phenylhexanal (16387-61-4)

Guidance literature:

With diisobutylaluminium hydride; In dichloromethane; toluene; at -78 ℃; for 0.25h;

DOI:10.1021/jm00080a005

Reference yield: 48.0%

acrolein (107-02-8,25068-14-8) → 6-phenylhexanal (16387-61-4)

Guidance literature:

With tri-n-butyl-tin hydride; tris(pyridine-2-carboxylato)manganese(III); In N,N-dimethyl-formamide; at 0 ℃; for 3h;

DOI:10.1246/cl.1993.1269

upstream raw materials:

5-Hexen-1-ol

iodobenzene

6-phenyl-hexanoic acid methyl ester

6-phenyl-1-hexanol

Downstream raw materials:

(E)-9-Phenyl-3-nonen-2-on

2-(methoxymethyl)-N-(6-phenylhexylidene)-1-pyrrolidinamine

5-(5-phenyl-pentyl)-4-tosyl-2-oxazoline

(Z)-methyl 2-(methoxymethylene)-8-phenyl-3-vinyloctanoate

Refernces

• 1、 Li, Jie,Qu, Shuanglin,Zhao, Wanxiang. "Rhodium-Catalyzed Remote C(sp3)?H Borylation of Silyl Enol Ethers". supporting information. p. 2360 - 2364. Retrieved 2020/01/02.
• 2、 Ota, Eisuke,Wang, Huaiju,Frye, Nils Lennart,Knowles, Robert R.. "A Redox Strategy for Light-Driven, Out-of-Equilibrium Isomerizations and Application to Catalytic C-C Bond Cleavage Reactions". supporting information. p. 1457 - 1462. Retrieved 2019/01/25.