1-(4-chlorophenyl)-1,2-propanedione dioxime

Base Information

• Chemical Name: 1-(4-chlorophenyl)-1,2-propanedione dioxime
• CAS No.: 123979-03-3
• Molecular Formula: C₉H₉ClN₂O₂
• Molecular Weight: 212.636
• Mol file: 123979-03-3.mol

Synonyms:1-(4-chlorophenyl)-1,2-propanedione dioxime

Chemical Property of 1-(4-chlorophenyl)-1,2-propanedione dioxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(4-chlorophenyl)-1,2-propanedione dioxime

There total 5 articles about 1-(4-chlorophenyl)-1,2-propanedione dioxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

1-(4-chlorophenyl)-2-(hydroxyimino)propan-1-one (56472-72-1) → 1-(4-chlorophenyl)-1,2-propanedione dioxime (123979-03-3)

Guidance literature:

With hydroxylamine hydrochloride; In methanol; water; for 3h; Reflux;

DOI:10.1016/j.ejmech.2017.03.017

Reference yield: 13.0%

2-bromo-1-(4-chlorophenyl)-1-butanone (1011-26-3) → 1-(4-chlorophenyl)-1,2-propanedione dioxime (123979-03-3) + (E)-1-(4-chlorophenyl)-2-hydroxyamino-1-hydroxyiminopropane + (Z)-1-(4-chlorophenyl)-2-hydroxyamino-1-hydroxyiminopropane (948908-05-2)

Guidance literature:

With sodium hydroxide; hydroxylamine hydrochloride; In methanol; water; for 8h; Heating;

DOI:10.1007/s11172-006-0374-0

Reference yield:

→ 1-(p-Chlorphenyl)-2-methyl-glyoxim (123979-03-3)

Guidance literature:

With sodium hydroxide; hydroxylamine;

DOI:10.1021/ja01309a039

upstream raw materials:

1-(4-chloro-phenyl)-propane-1,2-dione-1-oxime

2-bromo-1-(4-chlorophenyl)-1-butanone

4'-chloropropiophenone

1-(4-chlorophenyl)-2-(hydroxyimino)propan-1-one

Downstream raw materials:

3-(p-Chlorphenyl)-2-isoxazolin-4-on-oxim

4-Amino-3-(p-chlorphenyl)-5-chlorisoxazol

1-(4-chlorophenyl)-2-(hydroxyimino)propan-1-one

4-(4-chlorophenyl)-3-methyl-1,2,5-oxadiazole 2-oxide

Refernces

• 1、 Amitina,Grigor'ev,Tikhonov. "Reaction of Z isomers of alkylaromatic 1,2-hydroxylamino oximes with 1,2-diketones". . p. 1046 - 1051. Retrieved 2008/02/01.