Technology Process of 2-(3,5-bis(azidomethyl)phenoxy)ethyl 2-bromopropanoate
There total 4 articles about 2-(3,5-bis(azidomethyl)phenoxy)ethyl 2-bromopropanoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
triethylamine;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 4h;
DOI:10.1039/c0cc05478j
- Guidance literature:
-
Multi-step reaction with 4 steps
1: lithium aluminium tetrahydride / tetrahydrofuran / 16.5 h / 0 - 20 °C / Inert atmosphere
2: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 16 h / 0 - 20 °C / Darkness
3: tetrabutyl ammonium fluoride / tetrahydrofuran / 15 h / 20 °C
4: triethylamine / tetrahydrofuran / 4 h / 0 - 20 °C
With
lithium aluminium tetrahydride; diphenyl phosphoryl azide; tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine;
In
tetrahydrofuran; toluene;
DOI:10.1039/c0cc05478j
- Guidance literature:
-
Multi-step reaction with 3 steps
1: diphenyl phosphoryl azide; 1,8-diazabicyclo[5.4.0]undec-7-ene / toluene / 16 h / 0 - 20 °C / Darkness
2: tetrabutyl ammonium fluoride / tetrahydrofuran / 15 h / 20 °C
3: triethylamine / tetrahydrofuran / 4 h / 0 - 20 °C
With
diphenyl phosphoryl azide; tetrabutyl ammonium fluoride; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine;
In
tetrahydrofuran; toluene;
DOI:10.1039/c0cc05478j
