Technology Process of N-[4-(1,3,2-dithiarsolan-2-yl)phenyl]-6-[(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino]hexanamide
There total 8 articles about N-[4-(1,3,2-dithiarsolan-2-yl)phenyl]-6-[(7-nitrobenzo[c][1,2,5]oxadiazol-4-yl)amino]hexanamide which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 12h;
Inert atmosphere;
DOI:10.1002/chem.201300567
- Guidance literature:
-
With
potassium carbonate; triethylamine;
In
dichloromethane; acetonitrile;
at 20 ℃;
Inert atmosphere;
DOI:10.1002/chem.201300567
- Guidance literature:
-
Multi-step reaction with 3 steps
1: N-ethyl-N,N-diisopropylamine; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate / tetrahydrofuran; N,N-dimethyl-formamide / 20 °C / Inert atmosphere
2: trifluoroacetic acid / dichloromethane / 0.75 h / 20 °C
3: triethylamine; potassium carbonate / dichloromethane; acetonitrile / 20 °C / Inert atmosphere
With
potassium carbonate; triethylamine; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; N-[(dimethylamino)-3-oxo-1H-1,2,3-triazolo[4,5-b]pyridin-1-yl-methylene]-N-methylmethanaminium hexafluorophosphate;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1002/chem.201300567
