11-Desethyl Irinotecan

Base Information Edit

Chemical Name:11-Desethyl Irinotecan
CAS No.:103816-16-6
Molecular Formula:C₃₁H₃₄N₄O₆
Molecular Weight:558.634
Hs Code.:
UNII:JHM7B5DOV5
Nikkaji Number:J3.130.854B
Mol file:103816-16-6.mol

Synonyms:11-Desethyl Irinotecan;103816-16-6;7-Desethyl irinotecan;JHM7B5DOV5;[(19S)-19-ethyl-19-hydroxy-14,18-dioxo-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2(11),3,5,7,9,15(20)-heptaen-7-yl] 4-piperidin-1-ylpiperidine-1-carboxylate;10-(4-(1-Piperidino)-1-piperidinocarbonyloxy)camptothecin;(1,4'-Bipiperidine)-1'-carboxylic acid, 4-ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl ester, (S)-;(4S)-4-Ethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano(3',4':6,7)indolizino(1,2-b)quinolin-9-yl (1,4'-bipiperidine)-1'-carboxylate;Irinotecan 11-Desethyl Impurity;UNII-JHM7B5DOV5;7-Desethyl irinotecan [USP];SCHEMBL5652933;7-DESETHYL IRINOTECAN [USP IMPURITY];CS-0164101;(S)-4-Ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate;(S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate? (Irinotecan Impurity pound(c)

Suppliers and Price of 11-Desethyl Irinotecan

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
11-DesethylIrinotecan
1mg
$ 215.00

TRC
11-DesethylIrinotecan
10mg
$ 1695.00

Medical Isotopes, Inc.
11-DesethylIrinotecan
1 mg
$ 675.00

Total 5 raw suppliers

Chemical Property of 11-Desethyl Irinotecan Edit

Chemical Property:

Melting Point:>170°C (dec.)
Boiling Point:865.3±65.0 °C(Predicted)
PKA:11.20±0.20(Predicted)
Density:1.45±0.1 g/cm3(Predicted)
Storage Temp.:Refrigerator
Solubility.:Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:4
Exact Mass:558.24783482
Heavy Atom Count:41
Complexity:1160

Purity/Quality:

97% ^*data from raw suppliers

11-DesethylIrinotecan ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)OC(=O)N6CCC(CC6)N7CCCCC7)O
Isomeric SMILES:CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=CC5=C4)OC(=O)N6CCC(CC6)N7CCCCC7)O
Uses 11-Desethyl Irinotecan is an impurity of the DNA topoisomerase inhibitor Irinotecan (I767500).

Technology Process of 11-Desethyl Irinotecan

There total 5 articles about 11-Desethyl Irinotecan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%