2-Chlorobutanal

Base Information

• Chemical Name: 2-Chlorobutanal
• CAS No.: 28832-55-5
• Molecular Formula: C₄H₇ClO
• Molecular Weight: 106.552
• Mol file: 28832-55-5.mol

Synonyms:2-Chlorobutanal

Chemical Property of 2-Chlorobutanal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-Chlorobutanal

There total 2 articles about 2-Chlorobutanal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

N-butylidenebutylamine (130716-87-9) → 2-Chlorobutanal (28832-55-5) + 2,2-dichlorobutanal (23454-01-5) + N-butyl-butyramide (10264-16-1) + butyraldehyde (123-72-8) + N-butylamine (109-73-9,85404-21-3) + butyric acid (107-92-6)

Guidance literature:

With sodium persulfate; copper dichloride; In water; at 70 ℃; for 7.5h; Product distribution;

DOI:10.1007/BF00948513

Reference yield:

dibutylamine (111-92-2) → 2-Chlorobutanal (28832-55-5) + 2,2-dichlorobutanal (23454-01-5) + N-butyl-butyramide (10264-16-1) + butyric acid (107-92-6)

Guidance literature:

With sodium persulfate; copper dichloride; In water; at 70 - 80 ℃; for 7.5h; Product distribution;

DOI:10.1007/BF00948513

Reference yield: 94.0%

2-Chlorobutanal (28832-55-5) + N,N'-3,5-cyclohexadiene-1,2-diylidenebis(benzamide) (54748-01-5) → (R)-(2-ethyl-3-oxo-2,3-dihydroquinoxaline-1,4-diyl)bis(phenylmethanone)

Guidance literature:

With (5aR,10bS)-5a,10b-dihydro-2-(2,4,6-trimethylphenyl)-4H,6H-indeno[2,1-b]-1,2,4-triazolo[4,3-d]-1,4-oxazinium chloride; sodium acetate; In tetrahydrofuran; at 20 ℃; for 24h; enantioselective reaction; Schlenk technique; Molecular sieve; Inert atmosphere;

DOI:10.1021/acs.orglett.9b01520

upstream raw materials:

N-butylidenebutylamine

dibutylamine

Downstream raw materials:

1,1-dimethoxy-butan-2-ol

5-ethylthiazol-2-amine

1,1-Bis-aethoxycarbonylamino-2-chlor-butan

2-chloro-1-phenyl-butan-1-ol

Refernces