phenylene-1,2-diphosphonic acid tetraethyl ester

Base Information

• Chemical Name: phenylene-1,2-diphosphonic acid tetraethyl ester
• CAS No.: 71838-15-8
• Molecular Formula: C₁₄H₂₄O₆P₂
• Molecular Weight: 350.288
• Mol file: 71838-15-8.mol

Synonyms:phenylene-1,2-diphosphonic acid tetraethyl ester

Chemical Property of phenylene-1,2-diphosphonic acid tetraethyl ester

Chemical Property:

• Boiling Point: 427.7±28.0 °C(Predicted)
• Density: 1.17±0.1 g/cm3(Predicted)

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of phenylene-1,2-diphosphonic acid tetraethyl ester

There total 4 articles about phenylene-1,2-diphosphonic acid tetraethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

pyran-2-one (504-31-4) + tetraethyl ethynyldiphosphonate (4851-53-0) → phenylene-1,2-diphosphonic acid tetraethyl ester (71838-15-8)

Guidance literature:

In 1,2-dichloro-benzene; at 180 ℃; for 4h;

DOI:10.1016/S0040-4039(01)90465-4

Reference yield:

2-iodochlorobenzene (615-41-8) + sodium diethyl phosphite (2303-76-6,118080-94-7) → phenylene-1,2-diphosphonic acid tetraethyl ester (71838-15-8)

Guidance literature:

With sodium; In ammonia; at -33 ℃; Irradiation;

DOI:10.1021/jo00394a036

Reference yield:

pinacolone enolate anion (64723-95-1) + (2-iodophenyl)phosphonate de diethyle (71838-14-7) + diethyl phosphite (29800-93-9) → phenylene-1,2-diphosphonic acid tetraethyl ester (71838-15-8) + [2-(3,3-Dimethyl-2-oxo-butyl)-phenyl]-phosphonic acid diethyl ester

Guidance literature:

In ammonia; at -33 ℃; Product distribution; Irradiation; competitive reaction, at known concentrations; relative rate constants, half life;

DOI:10.1016/S0040-4020(01)97188-1

upstream raw materials:

pyran-2-one

tetraethyl ethynyldiphosphonate

pinacolone enolate anion

(2-iodophenyl)phosphonate de diethyle

Downstream raw materials:

C₂₄H₁₆N₂

C₈H₁₁P₂^(1-)*Na⁽¹⁺⁾

C₇H₉P₂^(1-)*Na⁽¹⁺⁾

C₆H₆P₂^(2-)*2Na⁽¹⁺⁾

Refernces

• 1、 Kyba, Even P.,Rines, Steven P.,Owens, Philip W.,Chou, Shang-Shing P.. "A NOVEL SYNTHESIS OF 1,2-DIPHOSPSORYLBENZENES". . p. 1875 - 1878. Retrieved 2007/10/02.