4-methyl-4-phenylpent-1ene

Base Information

• Chemical Name: 4-methyl-4-phenylpent-1ene
• CAS No.: 66622-39-7
• Molecular Formula: C₁₂H₁₆
• Molecular Weight: 160.259
• Mol file: 66622-39-7.mol

Synonyms:4-methyl-4-phenylpent-1ene

Chemical Property of 4-methyl-4-phenylpent-1ene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-methyl-4-phenylpent-1ene

There total 22 articles about 4-methyl-4-phenylpent-1ene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

cumyl acetate (3425-72-7) + allyl-trimethyl-silane (762-72-1) → 4-methyl-4-phenylpent-1ene (66622-39-7)

Guidance literature:

With triphenyl phosphite; chloro(1,5-cyclooctadiene)rhodium(I) dimer; tetrakis[3,5-bis(trifluoromethyl)phenyl]borate sodium; In 1,2-dichloro-ethane; for 1h; regioselective reaction; Reflux;

DOI:10.1002/adsc.201100202

Reference yield: 90.0%

cumenyl chloride (934-53-2) + allyl-trimethyl-silane (762-72-1) → 4-methyl-4-phenylpent-1ene (66622-39-7)

Guidance literature:

With zinc(II) chloride; In dichloromethane; at -78 ℃; for 60h;

Reference yield: 89.0%

1-methyl-1-phenylethyl alcohol (617-94-7) + allyl-trimethyl-silane (762-72-1) → 4-methyl-4-phenylpent-1ene (66622-39-7)

Guidance literature:

bismuth(III) chloride; In dichloromethane; at 80 ℃; for 2h;

DOI:10.1016/j.tetlet.2005.09.161

upstream raw materials:

4-chloro-4-methyl-1-pentetne

benzene

3-methyl-3-phenylbutanal

Methyltriphenylphosphonium bromide

Downstream raw materials:

2-amino-4-methyl-4-phenyl-pentanoic acid

3-methyl-3-phenylbutanal

(4-Bromo-3-ethoxy-1,1-dimethyl-butyl)-benzene

Refernces

• 1、 Holz, Julia,Pfeffer, Camilla,Zuo, Hualiang,Beierlein, Dennis,Richter, Gunther,Klemm, Elias,Peters, René. "In Situ Generated Gold Nanoparticles on Active Carbon as Reusable Highly Efficient Catalysts for a Csp3 ?Csp3 Stille Coupling". . p. 10330 - 10334. Retrieved 2019/06/27.
• 2、 Dao, Hai Thanh,Schneider, Uwe,Kobayashi, Shu. "Indium(i)-catalyzed alkyl-allyl coupling between ethers and an allylborane". supporting information; experimental part. p. 692 - 694. Retrieved 2011/03/22.