Technology Process of (E)-2-methoxy-3-nitro-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridine
There total 7 articles about (E)-2-methoxy-3-nitro-5-(((2,4,6-trimethoxystyryl)sulfonyl)methyl)pyridine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
piperidine; benzoic acid;
In
toluene;
for 3h;
Reflux;
Inert atmosphere;
Dean-Stark;
DOI:10.1021/jm4019614
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: sodium / 4 h / Reflux; Inert atmosphere
2.1: dibenzoyl peroxide; N-Bromosuccinimide / tetrachloromethane / 48 h / Inert atmosphere; Reflux
3.1: sodium carbonate / methanol / 1 h / 20 °C
4.1: dihydrogen peroxide; acetic acid / 6 h / 60 °C
5.1: water; sodium carbonate / methanol / 4 h / 20 °C
5.2: pH 2
6.1: piperidine; pyridine / 3 h / Inert atmosphere; Reflux
With
piperidine; pyridine; N-Bromosuccinimide; water; dihydrogen peroxide; sodium; sodium carbonate; acetic acid; dibenzoyl peroxide;
In
methanol; tetrachloromethane;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium carbonate / methanol / 1 h / 20 °C
2.1: dihydrogen peroxide; acetic acid / 6 h / 60 °C
3.1: water; sodium carbonate / methanol / 4 h / 20 °C
3.2: pH 2
4.1: piperidine; pyridine / 3 h / Inert atmosphere; Reflux
With
piperidine; pyridine; water; dihydrogen peroxide; sodium carbonate; acetic acid;
In
methanol;