830-79-5

Basic information

• Product Name: 2,4,6-Trimethoxybenzaldehyde
• Synonyms: PHLOROGLUCINOL ALDEHYDE TRIMETHYL ETHER;PHLOROGLUCINALDEHYDE TRIMETHYL ETHER;TIMTEC-BB SBB000351;Benzaldehyde, 2,4,6-trimethoxy-;AKOS BBS-00003255;2,4,6-TRIMETHOXYBENZALDEHYDE;2,4,6-Trimethoxybenzaldehyde98%;1-Formyl-2,4,6-trimethoxybenzene
• CAS NO: 830-79-5
• Molecular Formula: C₁₀H₁₂O₄
• Molecular Weight: 196.2
• EINECS: 212-598-2
• Product Categories: FINE Chemical & INTERMEDIATES;Aldehydes;blocks;Aromatic Aldehydes & Derivatives (substituted);BUILDING BLOCKS;C10 to C21;Carbonyl Compounds
• Mol File: 830-79-5.mol
• Article Data: 36

Chemical Properties

• Melting Point: 115-120 °C(lit.)
• Boiling Point: 293.08°C (rough estimate)
• Flash Point: 151.3 °C
• Appearance: Beige/Crystalline Powder
• Density: 1.2166 (rough estimate)
• Vapor Pressure: 9.37E-05mmHg at 25°C
• Refractive Index: 1.5550 (estimate)
• Storage Temp.: Keep in dark place,Sealed in dry,Room Temperature
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• Water Solubility: Insoluble in water.
• Sensitive: Air Sensitive
• BRN: 1956051
• CAS DataBase Reference: 2,4,6-Trimethoxybenzaldehyde(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4,6-Trimethoxybenzaldehyde(830-79-5)
• EPA Substance Registry System: 2,4,6-Trimethoxybenzaldehyde(830-79-5)

Safety Data

• Hazard Codes: C
• Statements: 36/37/38-34
• Safety Statements: 22-24/25-45-36/37/39-27-26
• WGK Germany: 3
• RTECS: CU8460200
• Hazardous Substances Data: 830-79-5(Hazardous Substances Data)

Usage

Chemical Properties

pink crystal power

Uses

2,4,6-Trimethoxybenzaldehyde was used in the preparation and characterization of three RNA-specific fluorescent probes and their use in live cell imaging. It was used as starting reagent for the regioselective synthesis of new (+/-)-8-alkyl-5,7-dihydroxy-4-(4-hydroxyphenyl)-3,4-dihydrocoumarins.

General Description

2,4,6-Trimethoxybenzaldehyde exhibits significant anti-candida activity.

InChI:InChI=1/C10H12O4/c1-12-7-4-9(13-2)8(6-11)10(5-7)14-3/h4-6H,1-3H3

Upstream product

• 621-23-8 1,2,3-trimethoxybenzene 
• 74-90-8 hydrogen cyanide 
• 103-70-8 Formanilid 
• 708-76-9 2-hydroxy-4,6-dimethoxybenzaldehyde 
• 74-88-4 methyl iodide 
• 877680-53-0 N-(chloromethyl)diformamide 
• 67-56-1 methanol 
• 68-12-2 N,N-dimethyl-formamide 
• 1415638-53-7 C₁₇H₁₉NO₅S 
• 32316-92-0 naphthalene-2-boronic acid 
• 108-73-6 3,5-dihydroxyphenol 
• 79-37-8 oxalyl dichloride 
• 40243-91-2 1,3,5-trimethoxy 2-vinyl benzene 
• 1535-67-7 difluoromethyl phenyl sulfide 

Downstream Products

• 13063-09-7 2,4,6-trimethoxy-cinnamic acid 
• 103852-72-8 1-(2,4,6-trimethoxy-phenyl)-ethanol 
• 670249-10-2 (2,4,6-trimethoxyphenyl)phenylmethanol 
• 708-76-9 2-hydroxy-4,6-dimethoxybenzaldehyde 
• 51903-38-9 2,4,6-trimethoxybenzaldehyde oxime 
• 570-02-5 2,4,6-trimethoxybenzoic acid 
• 14107-97-2 2,4,6-trimethoxytoluene 
• 61040-78-6 2,4,6-trimethoxybenzyl alcohol 
• 97024-78-7 4-(2,4,6-trimethoxy-phenyl)-but-3-en-2-one 
• 34552-30-2 3,4-diethyl-2-(2,4,6-trimethoxy-phenyl)-1-oxa-3-aza-spiro[4.5]decane 
• 116385-21-8 6-[1-pyrrolidinyl(2,4,6-trimethoxyphenyl)methyl]-1,3-benzodioxol-5-ol 
• 101932-26-7 3-Methyl-2-(2,4,6-trimethoxy-phenyl)-oxazolidine 
• 83522-16-1 2-(2,4,6-Trimethoxy-phenyl)-thiazolidine 
• 119963-68-7 1-Pyrrolidin-1-yl-2-[4-(2,4,6-trimethoxy-benzyl)-piperazin-1-yl]-ethanone 

Relevant articles and documents

Visible-Light-Mediated Late-Stage Sulfonylation of Boronic Acids via N-S Bond Activation of Sulfonamides

A visible-light-mediated late-stage arylation of N-S bonds in sulfonamides has been developed with using readily available imines as sulfonyl radical source. Diverse complex sulfones could be synthesized by prefunctionalizaiton and subsequent N-S bond ary

V2O5@TiO2 Catalyzed Green and Selective Oxidation of Alcohols, Alkylbenzenes and Styrenes to Carbonyls

The versatile application of different functional groups such as alcohols (1° and 2°), alkyl arenes, and (aryl)olefins to construct carbon-oxygen bond via oxidation is an area of intense research. Here, we report a reusable heterogeneous V2O5@TiO2 catalyzed selective oxidation of various functionalities utilizing different mild and eco-compatible oxidants under greener reaction conditions. The method was successfully applied for the alcohol oxidation, oxidative scission of styrenes, and benzylic C?H oxidation to their corresponding aldehydes and ketones. The utilization of mild and eco-friendly oxidizing reagents such as K2S2O8, H2O2 (30 % aq.), TBHP (70 % aq.), broad substrate scope, gram-scale synthesis, and catalyst recyclability are notable features of the developed protocol.

METHODS OF TREATING CANCER WITH SMALL MOLECULE NF-kB INHIBITORS

The present invention provides, inter alia, compounds capable of inhibiting NF-κB. Pharmaceutical compositions containing and methods of using the compounds are also provided herein. Also provided are methods and kits for treating cancer and solid tumors in a subject, as well as methods and kits for inducing cancer cell death and apoptosis of a cancer cell, all utilizing the NF-κB inhibitors described herein.