acridin-9-yl(phenyl)methanone

Base Information

• Chemical Name: acridin-9-yl(phenyl)methanone
• CAS No.: 37070-64-7
• Molecular Formula: C₂₀H₁₃NO
• Molecular Weight: 283.329
• Mol file: 37070-64-7.mol

Synonyms:acridin-9-yl(phenyl)methanone

Chemical Property of acridin-9-yl(phenyl)methanone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of acridin-9-yl(phenyl)methanone

There total 13 articles about acridin-9-yl(phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

acridine (260-94-6) + benzaldehyde (100-52-7) → acridin-9-yl(phenyl)methanone (37070-64-7)

Guidance literature:

With tert.-butylhydroperoxide; trifluoroacetic acid; In 1,2-dichloro-ethane; at 110 ℃; for 10h; Sealed tube;

DOI:10.1039/c5ob01763g

Reference yield: 81.0%

acridine (260-94-6) + benzoic acid hydrazide (613-94-5) → acridin-9-yl(phenyl)methanone (37070-64-7)

Guidance literature:

With dipotassium peroxodisulfate; Eosin Y; In water; dimethyl sulfoxide; at 20 ℃; for 12h; regioselective reaction; Irradiation; Green chemistry;

DOI:10.1039/d1ra07063k

Reference yield: 75.0%

acridine (260-94-6) + Benzoylformic acid (611-73-4) → acridin-9-yl(phenyl)methanone (37070-64-7)

Guidance literature:

With dipotassium peroxodisulfate; In water; acetonitrile; at 20 - 37 ℃; for 15h; regioselective reaction; Irradiation; Green chemistry;

DOI:10.1002/adsc.201800692

upstream raw materials:

acridine-9-carbonitrile

phenyllithium

acridine-9-carboxylic acid

benzaldehyde

Downstream raw materials:

(9,10-dihydro-acridin-9-yl)-phenyl-methanol

Refernces

• 1、 Ding, Hang,Xu, Kun,Zeng, Cheng-Chu. "Nickel-catalyzed electrochemical Minisci acylation of aromatic N-heterocycles with α-keto acids via ligand-to-metal electron transfer pathway". . p. 38 - 43. Retrieved 2019/11/14.
• 2、 Chen, Jiayu,Wan, Miao,Hua, Jing,Sun, Yi,Lv, Zheng,Li, Wei,Liu, Lei. "TBHP/TFA mediated oxidative cross-dehydrogenative coupling of N-heterocycles with aldehydes". . p. 11561 - 11566. Retrieved 2015/12/04.