1-benzenesulfonyl-4-iodoimidazole

Base Information

• Chemical Name: 1-benzenesulfonyl-4-iodoimidazole
• CAS No.: 183060-05-1
• Molecular Formula: C₉H₇IN₂O₂S
• Molecular Weight: 334.137
• Mol file: 183060-05-1.mol

Synonyms:1-benzenesulfonyl-4-iodoimidazole

Chemical Property of 1-benzenesulfonyl-4-iodoimidazole

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 1-benzenesulfonyl-4-iodoimidazole

There total 1 articles about 1-benzenesulfonyl-4-iodoimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

4-iodoimidazole (71759-89-2) + benzenesulfonyl chloride (98-09-9) → 1-benzenesulfonyl-4-iodoimidazole (183060-05-1)

Guidance literature:

With triethylamine; In tetrahydrofuran; for 16h; Ambient temperature;

DOI:10.1016/0040-4020(96)00823-X

Reference yield: 92.0%

N-tert-Butoxycarbonyl-1-amino-3-propyne (92136-39-5) + 1-benzenesulfonyl-4-iodoimidazole (183060-05-1) → [3-(1-benzenesulfonyl-1H-imidazol-4-yl)prop-2-ynyl]carbamic acid tert-butyl ester (269064-65-5)

Guidance literature:

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; diisobutylamine; In tetrahydrofuran; at 20 ℃; for 24h;

DOI:10.1021/jo991395b

Reference yield: 90.0%

tert-butyl N-[(tert-butoxy)carbonyl]-N-(prop-2-yn-1-yl)carbamate (141120-04-9) + 1-benzenesulfonyl-4-iodoimidazole (183060-05-1) → C22H27N3O6S

Guidance literature:

With copper(l) iodide; diisopropylamine; bis-triphenylphosphine-palladium(II) chloride; In tetrahydrofuran; for 24h; Ambient temperature;

DOI:10.1016/S0040-4039(98)00341-4

upstream raw materials:

4-iodoimidazole

benzenesulfonyl chloride

Downstream raw materials:

[3-(1-benzenesulfonyl-1H-imidazol-4-yl)prop-2-ynyl]carbamic acid tert-butyl ester

Refernces