2,2,2-trifluoroethyl morpholine-4-carboxylate

Base Information

• Chemical Name: 2,2,2-trifluoroethyl morpholine-4-carboxylate
• CAS No.: 923177-02-0
• Molecular Formula: C₇H₁₀F₃NO₃
• Molecular Weight: 213.157
• Mol file: 923177-02-0.mol

Synonyms:2,2,2-trifluoroethyl morpholine-4-carboxylate

Chemical Property of 2,2,2-trifluoroethyl morpholine-4-carboxylate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of 2,2,2-trifluoroethyl morpholine-4-carboxylate

There total 1 articles about 2,2,2-trifluoroethyl morpholine-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

morpholine (110-91-8,99108-56-2) + 2,2,2-trifluoroethyl chloroformate (27746-99-2) → 2,2,2-trifluoroethyl morpholine-4-carboxylate (923177-02-0)

Guidance literature:

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 6h;

DOI:10.1039/c4ra12425a

Reference yield:

2,2,2-trifluoroethyl morpholine-4-carboxylate (923177-02-0) → morpholine-4-carbohydrazide (29053-23-4)

Guidance literature:

With hydrazine; In ethanol; for 1.5h; Reflux;

DOI:10.1039/c4ra12425a

upstream raw materials:

morpholine

2,2,2-trifluoroethyl chloroformate

Downstream raw materials:

morpholine-4-carbohydrazide

Refernces