2,2'-DICHLORO DIPHENYL DISULFIDE

Base Information

• Chemical Name: 2,2'-DICHLORO DIPHENYL DISULFIDE
• CAS No.: 31121-19-4
• Molecular Formula: C12H8Cl2S2
• Molecular Weight: 287.234
• Hs Code.: 2930909090
• Mol file: 31121-19-4.mol

Synonyms:Disulfide,bis(o-chlorophenyl) (6CI,8CI);Bis(2-chlorophenyl) disulfide;Bis(o-chlorophenyl) disulfide;NSC 32024;

Chemical Property of 2,2'-DICHLORO DIPHENYL DISULFIDE

Chemical Property:

• Boiling Point: 352.589 °C at 760 mmHg
• Flash Point: 157.207 °C
• PSA: 50.60000
• Density: 1.43 g/cm³
• LogP: 5.79280
• Storage Temp.: Hygroscopic, Refrigerator, under inert atmosphere
• Solubility.: Chloroform (Slightly), DMSO (Slightly, Heated, Sonicated), Methanol (Slightly, H

Purity/Quality:

98% or more ^*data from raw suppliers

2,2''-DichloroDiphenylDisulfide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Uses: 2,2''-Dichloro Diphenyl Disulfide is a symmetrical disulfide synthesized from oxidation of thiols using various catalysts such as solid supported catalyst (Al2O3/KF), copper chloride, selenium ionic liquid.

Technology Process of 2,2'-DICHLORO DIPHENYL DISULFIDE

There total 17 articles about 2,2'-DICHLORO DIPHENYL DISULFIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-chlorothiphenol (6320-03-2) → bis(2-chlorobenzene)disulfide (31121-19-4)

Guidance literature:

With aluminum oxide; sodium iodate; In hexane; at 20 ℃; for 0.5h;

DOI:10.1039/a804667k

Reference yield: 94.0%

o-chloroaniline (95-51-2) → bis(2-chlorobenzene)disulfide (31121-19-4)

Guidance literature:

o-chloroaniline; With tetrafluoroboric acid; sodium nitrite; In water; acetone; at -20 - 0 ℃; for 0.333333h;

With carbon disulfide; tris(2,2-bipyridine)ruthenium(II) hexafluorophosphate; In dimethyl sulfoxide; at 20 ℃; for 6h; Irradiation;

DOI:10.3762/bjoc.13.91

Reference yield: 94.0%

Triphenylmethyl-2-chlorphenylsulfid (68191-59-3) → bis(2-chlorobenzene)disulfide (31121-19-4)

Guidance literature:

With water; copper(l) chloride; In dichloromethane; at 20 - 30 ℃; for 3h; ultrasonic irradiation;

DOI:10.1016/j.tetlet.2006.12.090

upstream raw materials:

1,4-dioxane

(2-chloro-phenyl)-phenyl disulfide

2-chlorothiphenol

(2-chloro-phenylsulfanyl)-acetic acid

Downstream raw materials:

C₁₂H₉Cl₂NO₂S₂

Monothiophosphorsaeure-O,O-dimethylester-S-<2-chlor-phenylester>

C₂₀H₂₂Cl₂S₂

(S)-5-((2-chlorophenylthio)methyl)pyrrolidin-2-one

Refernces

• 1、 Wei, Xiangxu,Zhong, Miao,Wang, Song,Li, Lexun,Song, Zi-Long,Zhang, Junmin,Xu, Jianqiang,Fang, Jianguo. "Synthesis and biological evaluation of disulfides as anticancer agents with thioredoxin inhibition". . . Retrieved 2021/03/24.
• 2、 Zhang, Guofu,Fan, Qiankun,Zhao, Yiyong,Wang, Huimin,Ding, Chengrong. "Dual Roles of Rongalite: Reductive Coupling Reaction to Construct Thiosulfonates Using Sulfonyl Hydrazides". . p. 81 - 85. Retrieved 2020/11/03.