9-Benzoyl-3-bromo-9H-carbazole

Base Information

• Chemical Name: 9-Benzoyl-3-bromo-9H-carbazole
• CAS No.: 177775-87-0
• Molecular Formula: C₁₉H₁₂BrNO
• Molecular Weight: 350.214
• Mol file: 177775-87-0.mol

Synonyms:(3-bromo-9H-carbazol-9-yl)(phenyl)methanone

Chemical Property of 9-Benzoyl-3-bromo-9H-carbazole

Chemical Property:

• Melting Point: 120.0 to 124.0 °C
• Boiling Point: 436.4±27.0 °C(Predicted)
• Density: 1.42±0.1 g/cm3(Predicted)

Purity/Quality:

98%, ^*data from raw suppliers

9-Benzoyl-3-bromo-9H-carbazole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-Benzoyl-3-bromo-9H-carbazole

There total 6 articles about 9-Benzoyl-3-bromo-9H-carbazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

3-bromo-9H-carbazole (1592-95-6) + benzoic acid (65-85-0,8013-63-6) → (3-bromo-9H-carbazol-9-yl)(phenyl)methanone (177775-87-0)

Guidance literature:

benzoic acid; With trifluoroacetic anhydride; at 20 ℃; for 0.333333h;

3-bromo-9H-carbazole; With phosphoric acid; at 20 ℃; for 1.33333h;

DOI:10.1039/c4ob00686k

Reference yield:

9-benzoyl-9H-carbazole (19264-68-7) + bromine (7726-95-6) → (3-bromo-9H-carbazol-9-yl)(phenyl)methanone (177775-87-0) + 1,2,3,6,8-pentabromo-carbazole + 9-benzoyl-3,6-dibromo-carbazole (912850-81-8) + 9-benzoyl-1,3,6-tribromo-carbazole

Guidance literature:

je nach Mengenverhaeltnissen und Reaktionsbedingungen;

Reference yield:

2-benzamido-5-bromobiphenyl (7511-41-3) → (3-bromo-9H-carbazol-9-yl)(phenyl)methanone (177775-87-0)

Guidance literature:

With tetrabutylammonium tetrafluoroborate; In water; Electrochemical reaction;

DOI:10.1002/chem.202003430

upstream raw materials:

3-bromo-9H-carbazole

benzoyl chloride

9-benzoyl-9H-carbazole

bromine

Downstream raw materials:

3-bromo-9H-carbazole

Refernces

• 1、 Kolli, Sunder Kumar,Prasad, Bagineni,Babu, P. Vijaya,Ashfaq, Mohd Ashraf,Ehtesham, Nasreen Z.,Raju, R. Ramesh,Pal, Manojit. "TFAA/H3PO4 mediated unprecedented N-acylation of carbazoles leading to small molecules possessing anti-proliferative activities against cancer cells". supporting information. p. 6080 - 6084. Retrieved 2014/08/05.