Technology Process of cis-1,2-Diphenylcyclohexane-1,2-diol
There total 18 articles about cis-1,2-Diphenylcyclohexane-1,2-diol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
cerium(III) chloride;
In
tetrahydrofuran;
at 0 - 20 ℃;
for 13h;
DOI:10.1055/s-1997-970
- Guidance literature:
-
With
titanium(IV) isopropylate; titanium; chloro-trimethyl-silane;
In
1,2-dimethoxyethane;
for 12h;
Heating;
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 47 percent / porcine pancreas lipase / various solvent(s) / 114 h / Ambient temperature; pH = 7.5; other enzymes, various reaction times; also enzyme -catalysed hydrolysis of (+/-)-5
2: 58 percent / N-chlorosuccinimide, dimethyl sulphide, triethylamine / toluene / 1.5 h / Ambient temperature
3: benzene / 23 h / Heating
With
N-chloro-succinimide; dimethylsulfide; triethylamine;
Porcine Pancreas Lipase;
In
toluene; benzene;
