2-IODO-PYRIDIN-4-YLAMINE

Base Information

• Chemical Name: 2-IODO-PYRIDIN-4-YLAMINE
• CAS No.: 88511-26-6
• Molecular Formula: C5H5 I N2
• Molecular Weight: 220.013
• Hs Code.: 2933399090
• Mol file: 88511-26-6.mol

Synonyms:Pyridine,4-amino-2-iodo- (6CI,7CI); 2-Iodopyridin-4-amine; 4-Amino-2-iodopyridine

Chemical Property of 2-IODO-PYRIDIN-4-YLAMINE

Chemical Property:

• PSA: 38.91000
• LogP: 1.84960

Purity/Quality:

99%min ^*data from raw suppliers

2-IODO-PYRIDIN-4-YLAMINE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-IODO-PYRIDIN-4-YLAMINE

There total 4 articles about 2-IODO-PYRIDIN-4-YLAMINE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-bromo-4-aminopyridine (7598-35-8) → 2-iodo-pyridin-4-ylamine (88511-26-6)

Guidance literature:

With copper(l) iodide; potassium iodide; In N,N-dimethyl-formamide; at 130 ℃; Inert atmosphere;

Reference yield:

2-iodo-4-nitropyridine N-oxide (52092-44-1) → 2-iodo-pyridin-4-ylamine (88511-26-6)

Guidance literature:

With ammonium hydroxide; iron(II) sulfate;

Reference yield:

2-iodopyridine (5029-67-4) → 2-iodo-pyridin-4-ylamine (88511-26-6)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid; aqueous hydrogen peroxide / Erwaermen des Reaktionsprodukts mit Salpetersaeure und Schwefelsaeure

2: FeSO₄; aqueous NH₃

With ammonium hydroxide; dihydrogen peroxide; iron(II) sulfate; acetic acid;

upstream raw materials:

2-iodo-4-nitropyridine N-oxide

2-iodopyridine

2-bromo-4-aminopyridine

Downstream raw materials:

2-iodoisonicotinonitrile

4-bromo-2-iodopyridine

2,4-diiodo-pyridine

4-amino-2-methoxypyridine

Refernces

• 1、 -. "PYRIMIDINES WITH TIE2 (TEK) ACTIVITY". Page/Page column 119. . Retrieved 2010/02/12.