Technology Process of 2-(2-Iodophenyl)ethyl 4-toluenesulfonate
There total 4 articles about 2-(2-Iodophenyl)ethyl 4-toluenesulfonate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
dmap; triethylamine;
In
dichloromethane;
at 20 ℃;
for 14.5h;
Inert atmosphere;
DOI:10.1021/acs.orglett.7b00402
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: potassium hydroxide / water; dimethyl sulfoxide / 1 h / 0 - 20 °C / Inert atmosphere
2.1: hydrogen; palladium 10% on activated carbon / methanol / 20.5 h / 20 °C / 760.05 Torr / Inert atmosphere
3.1: toluene-4-sulfonic acid / water / Inert atmosphere
3.2: Inert atmosphere
3.3: Inert atmosphere
4.1: dmap; triethylamine / dichloromethane / 14.5 h / 20 °C / Inert atmosphere
With
dmap; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; triethylamine; potassium hydroxide;
In
methanol; dichloromethane; water; dimethyl sulfoxide;
DOI:10.1021/acs.orglett.7b00402
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: hydrogen; palladium 10% on activated carbon / methanol / 20.5 h / 20 °C / 760.05 Torr / Inert atmosphere
2.1: toluene-4-sulfonic acid / water / Inert atmosphere
2.2: Inert atmosphere
2.3: Inert atmosphere
3.1: dmap; triethylamine / dichloromethane / 14.5 h / 20 °C / Inert atmosphere
With
dmap; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; triethylamine;
In
methanol; dichloromethane; water;
DOI:10.1021/acs.orglett.7b00402
