Technology Process of methyl 4-allyl-3-(tosyloxy)cyclohexanecarboxylate
There total 4 articles about methyl 4-allyl-3-(tosyloxy)cyclohexanecarboxylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1: H2 / 5percent Rh/Al2O3 / methanol / 24 h / 25 °C / 2585.7 Torr
2: H2SO4 / 20 h / Heating
3: Celite, pyridinium chlorochromate (PCC) / CH2Cl2 / 3 h / 25 °C
4: 1.) 2,2-dimethoxypropane, p-toluenesulfonic acid, 2.) NaBH4 / 1.) benzene, reflux, 2.) methanol, 0 deg C, 30 min
5: 55 percent / pyridine / 144 h / 25 °C
With
pyridine; sodium tetrahydroborate; Celite; sulfuric acid; hydrogen; toluene-4-sulfonic acid; 2,2-dimethoxy-propane; pyridinium chlorochromate;
Rh/Al2O3;
In
methanol; dichloromethane;
DOI:10.1021/jo00362a012
- Guidance literature:
-
Multi-step reaction with 3 steps
1: Celite, pyridinium chlorochromate (PCC) / CH2Cl2 / 3 h / 25 °C
2: 1.) 2,2-dimethoxypropane, p-toluenesulfonic acid, 2.) NaBH4 / 1.) benzene, reflux, 2.) methanol, 0 deg C, 30 min
3: 55 percent / pyridine / 144 h / 25 °C
With
pyridine; sodium tetrahydroborate; Celite; toluene-4-sulfonic acid; 2,2-dimethoxy-propane; pyridinium chlorochromate;
In
dichloromethane;
DOI:10.1021/jo00362a012
