C₃₁H₃₄N₂O₆

Base Information

• Chemical Name: C₃₁H₃₄N₂O₆
• CAS No.: 1613708-43-2
• Molecular Formula: C₃₁H₃₄N₂O₆
• Molecular Weight: 530.621
• Mol file: 1613708-43-2.mol

Synonyms:C₃₁H₃₄N₂O₆

Chemical Property of C₃₁H₃₄N₂O₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₁H₃₄N₂O₆

There total 9 articles about C₃₁H₃₄N₂O₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C20H22F3NO7S (1613708-42-1) + N-benzyloxycarbonyl-but-3-ynyl-1-amine (149965-78-6) → C31H34N2O6 (1613708-43-2)

Guidance literature:

With copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tri-tert-butyl phosphine; triethylamine; In hexane; acetonitrile; for 18h; Inert atmosphere; Reflux;

Reference yield:

(Z)-methyl 2-(tert-butyloxycarbonyl)amino-3-(1-(tert-butyldimethylsilyloxy)naphthalen-4-yl)acrylate → C31H34N2O6 (1613708-43-2)

Guidance literature:

Multi-step reaction with 5 steps

1: palladium 10% on activated carbon; hydrogen / ethanol / 16 h / 20 °C / 760.05 Torr

2: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.25 h / 0 °C

3: CHIRAEPAKAD columnS cm I_.Dx₅₀ cm L / isopropyl alcohol; n-heptane / Resolution of racemate

4: pyridine / dichloromethane / 2 h / 0 - 20 °C

5: triethylamine; copper(l) iodide; tri-tert-butyl phosphine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / acetonitrile; hexane / 18 h / Inert atmosphere; Reflux

With pyridine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tri-tert-butyl phosphine; palladium 10% on activated carbon; tetrabutyl ammonium fluoride; hydrogen; triethylamine; In tetrahydrofuran; ethanol; hexane; n-heptane; dichloromethane; isopropyl alcohol; acetonitrile;

Reference yield:

methyl 2-(tert-butoxycarbonylamino)-3-(4-(tert-butyldimethylsilyloxy)naphthalen-1-yl)propanoate (1613707-21-3) → C31H34N2O6 (1613708-43-2)

Guidance literature:

Multi-step reaction with 4 steps

1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.25 h / 0 °C

2: CHIRAEPAKAD columnS cm I_.Dx₅₀ cm L / isopropyl alcohol; n-heptane / Resolution of racemate

3: pyridine / dichloromethane / 2 h / 0 - 20 °C

4: triethylamine; copper(l) iodide; tri-tert-butyl phosphine; tetrakis(triphenylphosphine) palladium⁽⁰⁾ / acetonitrile; hexane / 18 h / Inert atmosphere; Reflux

With pyridine; copper(l) iodide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; tri-tert-butyl phosphine; tetrabutyl ammonium fluoride; triethylamine; In tetrahydrofuran; hexane; n-heptane; dichloromethane; isopropyl alcohol; acetonitrile;

upstream raw materials:

methyl 2-(tert-butoxycarbonylamino)-3-(4-(tert-butyldimethylsilyloxy)naphthalen-1-yl)propanoate

methyl 2-(tert-butoxycarbonylamino)-3-(4-hydroxynaphthalen-1-yl)propanoate

α-naphthol

(R)-methyl 2-(tert-butoxycarbonylamino)-3-(4-hydroxynaphthalen-1-yl)propanoate

Downstream raw materials:

C₃₀H₃₂N₂O₆

Refernces