(4-methoxyphenyl)(phenyl)methyl acetate

Base Information

• Chemical Name: (4-methoxyphenyl)(phenyl)methyl acetate
• CAS No.: 38513-66-5
• Molecular Formula: C16H16 O3
• Molecular Weight: 256.301
• Mol file: 38513-66-5.mol

Synonyms:Benzenemethanol,4-methoxy-a-phenyl-, acetate (9CI);Benzhydrol, 4-methoxy-, acetate (6CI); (?à)-(4-Methoxyphenyl)phenylmethyl acetate; NSC 404606

Chemical Property of (4-methoxyphenyl)(phenyl)methyl acetate

Chemical Property:

• Vapor Pressure: 2.18E-05mmHg at 25°C
• Boiling Point: 360.7°C at 760 mmHg
• Flash Point: 150.6°C
• Density: 1.113g/cm³

Purity/Quality:

99%min ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (4-methoxyphenyl)(phenyl)methyl acetate

There total 14 articles about (4-methoxyphenyl)(phenyl)methyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

p-benzylanizole (834-14-0) + acetic acid (64-19-7,77671-22-8) → (phenyl)(p-methoxyphenyl)methanol acetate (38513-66-5)

Guidance literature:

With 2,3-dicyano-5,6-dichloro-p-benzoquinone; In 1,2-dichloro-ethane; at 100 ℃; for 24h; Schlenk technique; Inert atmosphere;

DOI:10.1002/cssc.201200458

Reference yield: 92.0%

4-methoxybenzaldehyde-1,1-diacetate (14202-31-4) + phenylmagnesium bromide → (phenyl)(p-methoxyphenyl)methanol acetate (38513-66-5)

Guidance literature:

phenylmagnesium bromide; With manganese chloride bis(lithium chloride); In tetrahydrofuran; for 0.75h; cooling;

In tetrahydrofuran; at -10 ℃; for 0.333333h;

4-methoxybenzaldehyde-1,1-diacetate; In tetrahydrofuran; at -10 ℃; Further stages.;

Reference yield: 84.0%

1-(4-methoxyphenyl)-1-phenylmethanol (720-44-5) + acetic anhydride (108-24-7) → (phenyl)(p-methoxyphenyl)methanol acetate (38513-66-5)

Guidance literature:

With dmap; triethylamine; In dichloromethane; at 20 ℃; Inert atmosphere; Cooling with ice;

DOI:10.1002/anie.201702885

upstream raw materials:

1-(4-methoxyphenyl)-1-phenylmethanol

acetic anhydride

acetyl chloride

1-methoxy-4-(methoxy(phenyl)methyl)benzene

Downstream raw materials:

4-Methoxybenzophenone

4-methoxybenzhydryl benzoate

1-((4-methoxyphenyl)((4-methoxyphenyl)(phenyl)methoxy)methyl)benzene

(p-anisyl)phenylmethyl cation

Refernces

• 1、 Xu, Xiao-Long,Li, Zhi. "Catalytic Electrophilic Alkylation of p-Quinones through a Redox Chain Reaction". supporting information. p. 8196 - 8200. Retrieved 2017/06/30.
• 2、 Deshmukh, Madhukar B.,Jadhav, Sunil D.,Kadam, Shashikant V.. "Copper-catalyzed substitution reactions of acylal with organomanganese reagents". . p. 989 - 994. Retrieved 2008/09/18.