14202-31-4

Basic information

• Product Name: (4-methoxyphenyl)methanediyl diacetate
• Synonyms: (4-Methoxyphenyl)methylene diacetate; (Acetyloxy)(4-methoxyphenyl)methyl acetate; methanediol, 1-(4-methoxyphenyl)-, diacetate; p-Methoxyphenyl-methanediol diacetate
• CAS NO: 14202-31-4
• Molecular Formula: C₁₂H₁₄O₅
• Molecular Weight: 238.2366
• Mol File: 14202-31-4.mol
• Article Data: 106

Chemical Properties

• Boiling Point: 329.1°C at 760 mmHg
• Flash Point: 143.4°C
• Density: 1.17g/cm³
• Vapor Pressure: 0.000182mmHg at 25°C
• Refractive Index: 1.5
• CAS DataBase Reference: (4-methoxyphenyl)methanediyl diacetate(CAS DataBase Reference)
• NIST Chemistry Reference: (4-methoxyphenyl)methanediyl diacetate(14202-31-4)
• EPA Substance Registry System: (4-methoxyphenyl)methanediyl diacetate(14202-31-4)

Safety Data

• Hazardous Substances Data: 14202-31-4(Hazardous Substances Data)

Upstream product

• 108-24-7 acetic anhydride 
• 123-11-5 4-methoxy-benzaldehyde 
• 21185-25-1 p-methoxybenzal chloride 
• 10581-12-1 tetramethyl ammonium acetate 
• 104-01-8 4-Methoxyphenylacetic acid 
• 127-08-2 potassium acetate 
• 116274-76-1 6-(4-Methoxy-phenyl)-6,7-dihydro-5H-5,7,7a,13-tetraaza-benzo[3,4]cyclohepta[1,2-b]naphthalen-8-one 
• 104-93-8 p-methylanizole 
• 64-19-7 acetic acid 
• 555-16-8 4-nitrobenzaldehdye 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 99-61-6 3-nitro-benzaldehyde 

Downstream Products

• 874-90-8 4-methoxybenzonitrile 
• 16031-55-3 1-(4-methoxyphenyl)prop-1-yl acetate 
• 123-11-5 4-methoxy-benzaldehyde 
• 110327-10-1 1-acetoxy-1-(4'-methoxyphenyl)-2-methylpropane 
• 99843-19-3 acetoxy-(4-methoxy-phenyl)-acetonitrile 
• 24588-72-5 2-(4-methoxyphenyl)-1,3-dithiane 
• 23837-15-2 1-(bis(ethylthio)methyl)-4-methoxybenzene 
• 6712-20-5 2-(4-methoxyphenyl)-[1,3]dithiolane 
• 6275-32-7 (2E,6E)-2,6-bis(4-methoxybenzylidene)cyclohexanone 
• 5447-53-0 (2E,5E)-2,5-bis(4-methoxybenzylidene)cyclopentanone 
• 140-11-4 Benzyl acetate 
• 161374-07-8 ethyl 4-(4-methoxyphenyl)-6-methyl-1,2,3,4-tetrahydropyrimidin-2-one-5-carboxylate 
• 24165-60-4 1-(4-methoxyphenyl)but-3-en-1-ol 
• 38513-66-5 (phenyl)(p-methoxyphenyl)methanol acetate 

Relevant articles and documents

Lithium chloride-assisted chemoselective conversion of aldehydes into geminal diacetates under solvent-free conditions

A mixture of lithium chloride and acetic anhydride was used for converting aldehydes into geminal diacetates under solvent-free conditions in high yields. Copyright Taylor & Francis, Inc.

Conversion of aldehydes into geminal dicarboxylates (acylals) catalyzed by lithium tetrafluoroborate

A variety of aldehydes react with acid anhydrides in the presence of a catalytic amount of lithium tetrafluoroborate to afford the corresponding geminal dicarboxylates (acylals) in good to excellent yields.

An efficient method for the synthesis of acylals from aldehydes under solvent-free conditions catalyzed by antimony trichloride

A mild and efficient method has been developed for the preparation of acylals from aldehydes catalyzed by antimony trichloride under solvent-free conditions in very good to excellent yields. The easy availability, low cost, and ease of handling of the catalyst make this procedure especially attractive for large-scale synthesis. Copyright Taylor & Francis Group, LLC.

Application of poly(Vinylbenzyltrimethylammonium tribromide) resin as an efficient polymeric catalyst in the acetalization and diacetylation of benzaldehydes

The applications of a new supported tribromide reagent (poly(vinylbenzyltrimethylammonium tribromide) resin) were reported. This supported tribromide resin was used as a catalyst in the acetalization and diacetylation of benzaldehydes under mild conditions with high efficiency. The effects of solvents, and amount of the supported tribromide resin on the reactions were investigated. Under the optimal conditions, most of acetal and 1,1-diacetates of benzaldehydes were selectively obtained in excellent yields.

Chemoselective synthesis of 1,1-diacetates under solvent-free condition using efficient heterogeneous ecofriendly catalyst: P2O5/kaolin

An efficient and chemoselective method for the preparation of acylals from different aldehydes and acetic anhydride using.....kaolin supported catalyst (P2O5). under solvent-free conditions is described herein. The present protocol offers several advantages including use of inexpensive and non-toxic catalyst support i.e., natural kaolin. Preparation of the supported catalyst is easy, the process is simple in operation, maintaining solvent free conditions, with short reaction times, high yields and affording selective protection of aldehyde in presence of ketone.

Tungstosulfonic acid as an efficient solid acid catalyst for acylal synthesis for the protection of the aldehydic carbonyl group

Tungstosulfonic acid (TSA) has been found to be an efficient solid acid catalyst for the protection of aldehydic carbonyl groups by geminal diacetate (acylal) formation following the nucleophilic addition of acetic anhydride under neat conditions as well as in a solvent. The TSA catalyst is fully characterized by infrared spectroscopy, wide-angle X-ray scattering analysis, and scanning electron microscopy with energy dispersive X-ray spectroscopy. The deprotection of acylals to corresponding aldehydes has also been investigated under the similar conditions. The catalyst can be reused seven times without a significant loss of activity. In addition, no chromatographic separations are needed to obtain the desired products. This method is a green approach for the chemoselective protection of aldehydes in the presence of ketones.