24588-72-5

Basic information

• Product Name: 4-Methoxybenzaldehyde trimethylenedithioacetal
• Synonyms: 2-(4-Methoxyphenyl)-1,3-dithiane;4-Methoxybenzaldehyde trimethylenedithioacetal
• CAS NO: 24588-72-5
• Molecular Formula: C₁₁H₁₄OS₂
• Molecular Weight: 226.3583
• Mol File: 24588-72-5.mol
• Article Data: 89

Chemical Properties

• Melting Point: 121 °C
• Boiling Point: 366.6°Cat760mmHg
• Flash Point: 175.5°C
• Appearance: /
• Density: 1.169g/cm³
• Vapor Pressure: 3.05E-05mmHg at 25°C
• Refractive Index: 1.596
• Solubility: soluble in Acetone
• CAS DataBase Reference: 4-Methoxybenzaldehyde trimethylenedithioacetal(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Methoxybenzaldehyde trimethylenedithioacetal(24588-72-5)
• EPA Substance Registry System: 4-Methoxybenzaldehyde trimethylenedithioacetal(24588-72-5)

Safety Data

• Hazardous Substances Data: 24588-72-5(Hazardous Substances Data)

Usage

General Description

4-Methoxybenzaldehyde trimethylenedithioacetal is a chemical compound with the molecular formula C12H14O2S2. It is a liquid at room temperature and is commonly used as an organic synthesis intermediate. 4-Methoxybenzaldehyde trimethylenedithioacetal is often used in the production of pharmaceuticals, fragrances, and other fine chemicals. It has a strong odor and can be irritating to the skin and respiratory system. The chemical properties of 4-Methoxybenzaldehyde trimethylenedithioacetal make it useful in a wide range of industrial applications, and it is an important building block in the production of various synthetic compounds.

InChI:InChI=1/C11H14OS2/c1-12-10-5-3-9(4-6-10)11-13-7-2-8-14-11/h3-6,11H,2,7-8H2,1H3

Upstream product

• 109-80-8 1.3-propanedithiol 
• 123-11-5 4-methoxy-benzaldehyde 
• 544-25-2 Cyclohepta-1,3,5-triene 
• 100-09-4 4-methoxybenzoic acid 
• 2186-92-7 p-Anisaldehyde dimethyl acetal 
• 22391-03-3 2-(4-methoxyphenyl)-1,3-oxathiolane 
• 2403-58-9 4-methoxybenzaldehyde diethylacetal 
• 2403-50-1 2-(4-methoxyphenyl)-1,3-dioxolane 
• 5689-71-4 2-(4-methoxy-phenyl)-[1,3]dioxane 
• 682360-46-9 2-(1,3-dithian-2-ylidene)-3-oxobutanoic acid 
• 505-23-7 1,3 dithiane 
• 69278-13-3 2-(4-methoxyphenyl)-1,3-dithiane 1-oxide 
• 23837-15-2 1-(bis(ethylthio)methyl)-4-methoxybenzene 
• 6712-20-5 2-(4-methoxyphenyl)-[1,3]dithiolane 

Downstream Products

• 74955-10-5 [2-(4-Methoxy-phenyl)-[1,3]dithian-2-yl]-phenyl-methanone oxime 
• 129959-16-6 8-Methoxy-1-<2-(4'-methoxyphenyl)-1,3-dithiane-2-yl>-isoquinoline 
• 123-11-5 4-methoxy-benzaldehyde 
• 79032-16-9 1,2-dithiolane 1-oxide 
• 111997-78-5 2-(4-Methoxyphenyl)-1,3-dithian-2-ylium-tribromid 
• 156387-49-4 Bis<3-(4-methoxybenzoylsulfanyl)propyl> disulfide 
• 128155-61-3 2-(4-Methoxyphenyl)-2-thiomethoxy-1,3-dithiane 
• 215813-56-2 2,2'-Bis-(4-methoxy-phenyl)-[2,2']bi[[1,3]dithianyl] 
• 5689-71-4 2-(4-methoxy-phenyl)-[1,3]dioxane 
• 121-98-2 methyl 4-methoxybenzoate 
• 100-09-4 4-methoxybenzoic acid 
• 461051-85-4 2-(4-methoxyphenyl)-2-triethylsilyl-1,3-dithiane 
• 41841-01-4 1-(2-chlorophenyl)-2-(4-methoxyphenyl)ethane-1,2-dione 
• 1456628-12-8 3-[2-(4-methoxyphenyl)-1,3-dithian-2-yl]propanenitrile 

Relevant articles and documents

Visible-Light Mediated Tryptophan Modification in Oligopeptides Employing Acylsilanes

A method for the selective tryptophan modification and labelling of tryptophan-containing peptides is described. Photoirradiation of acylsilanes generates reactive siloxycarbenes which undergo H?N-insertion into the indole moiety of tryptophan to give stable silyl protected hemiaminals. This method is successfully applied to chemically modify various tryptophan containing oligopeptides. The method enables the selective introduction of alkynes to peptides that are eligible for further alkyne-azide click chemistry. In addition, the dansyl fluorophore can be conjugated to a peptide using this approach.

Highly ordered mesoporous functionalized pyridinium protic ionic liquid framework as a highly efficient catalytic system in chemoselective thioacetalization of carbonyl compounds under solvent-free conditions

Dithioacetals are a well-known class of organic compounds as both protecting group for the carbonyl compounds and valuable synthons for organic synthesis. Polysiloxane acidic ionic liquids containing pyridinium trifluoroacetate salts (PMO-Py-IL) as organi

Photocatalytic Reductive Radical-Polar Crossover for a Base-Free Corey–Seebach Reaction

A metal-free generation of carbanion nucleophiles is of prime importance in organic synthesis. Herein we report a photocatalytic approach to the Corey–Seebach reaction. The presented method operates under mild redox-neutral and base-free conditions giving the desired product with high functional group tolerance. The reaction is enabled by the combination of photo- and hydrogen atom transfer (HAT) catalysis. This catalytic merger allows a C?H to carbanion activation by the abstraction of a hydrogen atom followed by radical reduction. The generated nucleophilic intermediate is then capable of adding to carbonyl electrophiles. The obtained dithiane can be easily converted to the valuable α-hydroxy carbonyl in a subsequent step. The proposed reaction mechanism is supported by emission quenching, radical–radical homocoupling and deuterium labeling studies as well as by calculated redox-potentials and bond strengths.