BIPHENYL-3-CARBOXYLIC ACID HYDRAZIDE

Base Information

• Chemical Name: BIPHENYL-3-CARBOXYLIC ACID HYDRAZIDE
• CAS No.: 709653-55-4
• Molecular Formula: C₁₃H₁₂N₂O
• Molecular Weight: 212.251
• Hs Code.: 2928000090
• Mol file: 709653-55-4.mol

Synonyms:BIPHENYL-3-CARBOXYLIC ACID HYDRAZIDE

Chemical Property of BIPHENYL-3-CARBOXYLIC ACID HYDRAZIDE

Chemical Property:

• PSA: 55.12000
• LogP: 3.04830

Purity/Quality:

98%min ^*data from raw suppliers

3-phenylbenzohydrazide ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of BIPHENYL-3-CARBOXYLIC ACID HYDRAZIDE

There total 8 articles about BIPHENYL-3-CARBOXYLIC ACID HYDRAZIDE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

biphenyl-3-carboxylic acid ethyl ester (19926-50-2) → 3-biphenylcarboxylic acid hydrazide (709653-55-4)

Guidance literature:

With hydrazine hydrate; In ethanol; at 80 ℃; for 5h;

Reference yield: 91.0%

→ 3-biphenylcarboxylic acid hydrazide (709653-55-4)

Guidance literature:

Reference yield: 85.0%

methyl 3-phenylbenzoate (16606-00-1) → 3-biphenylcarboxylic acid hydrazide (709653-55-4)

Guidance literature:

With hydrazine hydrate; In ethanol; for 3h; Reflux;

DOI:10.1021/jm301032j

upstream raw materials:

ethyl 3-bromobenzoate

phenylboronic acid

biphenyl-3-carboxylic acid ethyl ester

methyl 3-phenylbenzoate

Refernces

• 1、 Becker, Katja,Benvenuti, Manuela,Bossis, Guillaume,Conde, Pierre-Alexis,Crowder, Michael W.,Dillenberger, Melissa,Docquier, Jean-Denis,Gavara, Laurent,Hernandez, Jean-Fran?ois,Legru, Alice,Mangani, Stefano,Pozzi, Cecilia,Sannio, Filomena,Tassone, Giusy,Thomas, Caitlyn A.,Verdirosa, Federica. "1,2,4-Triazole-3-thione compounds with a 4-ethyl alkyl/aryl sulfide substituent are broad-spectrum metallo-β-lactamase inhibitors with re-sensitization activity". supporting information. . Retrieved 2021/10/12.
• 2、 Priebbenow, Daniel L.,Leaver, David J.,Nguyen, Nghi,Cleary, Benjamin,Lagiakos, H. Rachel,Sanchez, Julie,Xue, Lian,Huang, Fei,Sun, Yuxin,Mujumdar, Prashant,Mudududdla, Ramesh,Varghese, Swapna,Teguh, Silvia,Charman, Susan A.,White, Karen L.,Shackleford, David M.,Katneni, Kasiram,Cuellar, Matthew,Strasser, Jessica M.,Dahlin, Jayme L.,Walters, Michael A.,Street, Ian P.,Monahan, Brendon J.,Jarman, Kate E.,Jousset Sabroux, Helene,Falk, Hendrik,Chung, Matthew C.,Hermans, Stefan J.,Downer, Natalie L.,Parker, Michael W.,Voss, Anne K.,Thomas, Tim,Baell, Jonathan B.. "Discovery of acylsulfonohydrazide-derived inhibitors of the lysine acetyltransferase, kat6a, as potent senescence-inducing anti-cancer agents". . p. 4655 - 4684. Retrieved 2020/06/08.