dibenzo[a,j]acridin-14(7H)-one

Base Information

• Chemical Name: dibenzo[a,j]acridin-14(7H)-one
• CAS No.: 105467-74-1
• Molecular Formula: C₂₁H₁₃NO
• Molecular Weight: 295.34
• Mol file: 105467-74-1.mol

Synonyms:

Chemical Property of dibenzo[a,j]acridin-14(7H)-one

Chemical Property:

• Vapor Pressure: 1.03E-11mmHg at 25°C
• Boiling Point: 539.7°C at 760 mmHg
• Flash Point: 208.7°C
• Density: 1.301g/cm³

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of dibenzo[a,j]acridin-14(7H)-one

There total 12 articles about dibenzo[a,j]acridin-14(7H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

dibenzacridine N-oxide (1163-05-9) → 7H-dibenzacridone (105467-74-1)

Guidance literature:

With acetic anhydride; for 4h; Heating;

DOI:10.1021/jo00382a017

Reference yield: 66.0%

carbon monoxide (201230-82-2) + 2,2'-dinaphthylamine (532-18-3) → 7H-dibenzacridone (105467-74-1)

Guidance literature:

With di-tert-butyl peroxide; palladium dichloride; In dimethyl sulfoxide; at 100 ℃; for 24h; Schlenk technique;

Reference yield:

1-dimethylaminomethyl-naphthalen-2-ol (5419-02-3) → 7H-dibenzacridone (105467-74-1)

Guidance literature:

Multi-step reaction with 4 steps

1: 0.5 g / 0.5 h / 260 - 280 °C

2: 83 percent / 10percent Pd/C / various solvent(s) / 8 h / 190 °C

3: 84 percent / m-chloroperbenzoic acid / CHCl₃ / 5 h / Heating

4: 67 percent / (CH₃CO)2O / 4 h / Heating

With acetic anhydride; 3-chloro-benzenecarboperoxoic acid; palladium on activated charcoal; In chloroform;

DOI:10.1021/jo00382a017

upstream raw materials:

2-(N-[2]naphthyl-benzimidoyloxy)-[1]naphthoic acid methyl ester

dibenzacridine N-oxide

3-hydroxy-1-methylbenzoquinoline

1-dimethylaminomethyl-naphthalen-2-ol

Refernces

• 1、 -. "Method for synthesizing acridone derivatives by means of palladium-copper co-catalysis". Paragraph 0074; 00075; 0076; 0077. . Retrieved 2017/02/09.
• 2、 Rosario, Christopher A.,Holder, Gerald M.,Duke, Colin C.. "Synthesis of Potential Metabolites of Dibenzacridine: Dihydro Diols and Phenols". . p. 1064 - 1072. Retrieved 2007/10/02.