Technology Process of 2-(pyren-1-ylmethylamino)ethyl 3-N-(4-(azidomethyl)benzyl)-aminopropyl ether
There total 11 articles about 2-(pyren-1-ylmethylamino)ethyl 3-N-(4-(azidomethyl)benzyl)-aminopropyl ether which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
methanol; sodium tetrahydroborate;
In
tetrahydrofuran;
at 0 ℃;
for 1h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1: hydrogen; ammonia / palladium on activated charcoal / tetrahydrofuran; methanol / 1 h / 760.05 Torr
2: methanol
3: sodium tetrahydroborate; methanol / 2 h / 0 °C
4: trifluoroacetic acid / dichloromethane / 1 h / 0 °C / Inert atmosphere
5: tetrahydrofuran; methanol
6: sodium tetrahydroborate; methanol / tetrahydrofuran / 1 h / 0 °C
With
methanol; sodium tetrahydroborate; ammonia; hydrogen; trifluoroacetic acid;
palladium on activated charcoal;
In
tetrahydrofuran; methanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 8 steps
1: hydrogenchloride; water / tetrahydrofuran / 1 h
2: hydrogen bromide / dichloromethane; acetic acid
3: sodium azide / N,N-dimethyl-formamide / 1 h / 60 °C
4: methanol
5: sodium tetrahydroborate; methanol / 2 h / 0 °C
6: trifluoroacetic acid / dichloromethane / 1 h / 0 °C / Inert atmosphere
7: tetrahydrofuran; methanol
8: sodium tetrahydroborate; methanol / tetrahydrofuran / 1 h / 0 °C
With
hydrogenchloride; methanol; sodium tetrahydroborate; sodium azide; water; hydrogen bromide; trifluoroacetic acid;
In
tetrahydrofuran; methanol; dichloromethane; acetic acid; N,N-dimethyl-formamide;
