1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt

Base Information

• Chemical Name: 1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt
• CAS No.: 20958-76-3
• Molecular Formula: C₁₅H₁₂N₂O
• Molecular Weight: 236.273
• Mol file: 20958-76-3.mol

Synonyms:1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt

Chemical Property of 1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt

There total 3 articles about 1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

benzophenone α-chloroacetylhydrazone (29043-58-1) → 1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt (20958-76-3)

Guidance literature:

With sodium hydride; In tetrahydrofuran; for 24h; Ambient temperature;

DOI:10.1021/ja00416a009

Reference yield:

benzophenone hydrazone (5350-57-2) → 1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt (20958-76-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 89 percent / pyridine / CH₂Cl₂ / 0.25 h / Heating

2: 98 percent / 53percent sodium hydride / tetrahydrofuran / 24 h / Ambient temperature

With pyridine; sodium hydride; In tetrahydrofuran; dichloromethane;

DOI:10.1021/ja00416a009

Reference yield:

→ 1-(diphenylmethylene)-3-oxo-1,2-diazetidinium hydroxide, inner salt (20958-76-3)

Guidance literature:

Benzophenon-chloracetyl-hydrazon, K-tert.-Butylat (Dehydrochlorierung; Mechanismus);

DOI:10.1021/ja01021a041

upstream raw materials:

benzophenone α-chloroacetylhydrazone

benzophenone hydrazone

Downstream raw materials:

3-Oxo-5-(3-oxo-[1,2]diazetidin-1-yl)-5,5-diphenyl-pentanoic acid methyl ester

(5aS,10aR)-1,6-Dioxo-3,3,8,8-tetraphenyl-tetrahydro-dipyrrolo[1,2-a;1',2'-d]pyrazine-5a,10a-dicarboxylic acid dimethyl ester

C₂₆H₂₇NO₃

2-Diazo-3-oxo-5-(3-oxo-[1,2]diazetidin-1-yl)-5,5-diphenyl-pentanoic acid methyl ester

Refernces

• 1、 Taylor, Edward C.,Haley, Neil F.,Clemens, Robert J.. "Synthesis and properties of 3-oxo-1,2-diazetidinium ylides". . p. 7743 - 7752. Retrieved 2007/12/18.