N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide

Base Information

• Chemical Name: N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide
• CAS No.: 103802-26-2
• Molecular Formula: C₁₆H₁₁FN₂O₃
• Molecular Weight: 298.273
• Mol file: 103802-26-2.mol

Synonyms:N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide

Chemical Property of N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide

Chemical Property:

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Technology Process of N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide

There total 1 articles about N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-fluoro-4-hydroxy-quinoline-3-carboxylic acid (343-10-2) + N-Phenylhydroxylamine (100-65-2) → N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide (103802-26-2)

Guidance literature:

With pyridine; thionyl chloride; In dichloromethane; benzene;

Reference yield:

azodicarboxylic acid ethyl ester + N,4-dihydroxy-6-fluoro-N-phenyl-3-quinoline carboxamide (103802-26-2) → 8-fluoro-2-phenyl isoxazolo(4,5-c)quinolin-3(2H)-one

Guidance literature:

With triphenylphosphine; In N-methyl-acetamide;

upstream raw materials:

6-fluoro-4-hydroxy-quinoline-3-carboxylic acid

N-Phenylhydroxylamine

Refernces