Tributyl(4-methoxyphenyl)stannane

Base Information

• Chemical Name: Tributyl(4-methoxyphenyl)stannane
• CAS No.: 70744-47-7
• Molecular Formula: C19H34 O Sn
• Molecular Weight: 397.188
• Hs Code.: 2931200000
• DSSTox Substance ID: DTXSID00376297
• Mol file: 70744-47-7.mol

Synonyms:70744-47-7;TRIBUTYL(4-METHOXYPHENYL)STANNANE;Tributyl-(4-methoxyphenyl)stannane;4-(Tributylstannyl)anisole;Stannane,tributyl(4-methoxyphenyl)-;Stannane, tributyl(4-methoxyphenyl)-;(4-Methoxyphenyl)tributylstannane;Tributyl-(4-methoxy-phenyl)-stannane;SCHEMBL1097013;DTXSID00376297;LIILCIIZVMZTSC-UHFFFAOYSA-N;(p-methoxyphenyl)tri-n-butylstannane;MFCD01114690;AKOS022193641;AS-2948;FT-0763621;H10009;A854598

Chemical Property of Tributyl(4-methoxyphenyl)stannane

Chemical Property:

• Vapor Pressure: 3.51E-06mmHg at 25°C
• Boiling Point: 398℃
• Flash Point: 195℃
• PSA: 9.23000
• LogP: 5.75130
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 11
• Exact Mass: 398.163168
• Heavy Atom Count: 21
• Complexity: 224

Purity/Quality:

98%,99%, ^*data from raw suppliers

4-(Tributylstannyl)anisole ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC[Sn](CCCC)(CCCC)C1=CC=C(C=C1)OC

Technology Process of Tributyl(4-methoxyphenyl)stannane

There total 17 articles about Tributyl(4-methoxyphenyl)stannane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

1-bromo-4-methoxy-benzene (104-92-7) + tributyltin chloride (1461-22-9) → (p-methoxyphenyl)tri-n-butylstannane (70744-47-7)

Guidance literature:

With trifluoroacetic acid; cobalt(II) bromide; zinc; In acetonitrile; CoBr2 and Zn dust activated with CF3CO2H reacted for 5 min with allyl chloride in MeCN, aryl halide and tributylstannyl chloride added simultaneously in MeCN at room temp., stirred for 0.5 h at 50°C;

DOI:10.1039/b417326k

Reference yield: 94.0%

1-bromo-4-methoxy-benzene (104-92-7) + bis(tri-n-butyltin) (813-19-4) → (p-methoxyphenyl)tri-n-butylstannane (70744-47-7)

Guidance literature:

With tetrakis(triphenylphosphine) palladium⁽⁰⁾; tetrabutylammomium bromide; potassium hydroxide; In water; at 100 ℃; for 0.0666667h; Reagent/catalyst; Solvent; Microwave irradiation;

DOI:10.1002/ejoc.201402404

Reference yield: 91.0%

4-methoxyphenylboronic acid (5720-07-0) + tributyltin methoxide (1067-52-3) → (p-methoxyphenyl)tri-n-butylstannane (70744-47-7)

Guidance literature:

In neat (no solvent); at 100 ℃; for 1h; Inert atmosphere;

DOI:10.1016/j.tet.2015.01.048

upstream raw materials:

4-chloromethoxybenzene

tri-n-butyl-tin hydride

1-bromo-4-methoxy-benzene

tributyltin chloride

Downstream raw materials:

N-(4-methoxybenzyl)pyrrolidine

4-(4-methoxy-benzyl)-morpholine

2-(4-methoxyphenyl)-tetrahydro-2H-pyran

3-(4-methoxyphenyl)formylbenzaldehyde

Refernces

• 1、 Nocentini, Alessio,Supuran, Claudiu T.,?alubovskis, Raivis,Domra?eva, Ilona,Grandāne, Aiga. "Development of oxathiino[6,5-b]pyridine 2,2-dioxide derivatives as selective inhibitors of tumor-related carbonic anhydrases IX and XII". supporting information. . Retrieved 2020/05/25.
• 2、 Akram, Manjur O.,Shinde, Popat S.,Chintawar, Chetan C.,Patil, Nitin T.. "Gold(i)-catalyzed cross-coupling reactions of aryldiazonium salts with organostannanes". supporting information. p. 2865 - 2869. Retrieved 2018/05/03.