5-Amino-6-chloroquinoline

Base Information

• Chemical Name: 5-Amino-6-chloroquinoline
• CAS No.: 341010-40-0
• Molecular Formula: C₉H₇ClN₂
• Molecular Weight: 178.621
• Hs Code.: 2933499090
• ChEMBL ID: CHEMBL4860099
• DSSTox Substance ID: DTXSID60485177
• Wikidata: Q72434956
• Mol file: 341010-40-0.mol

Synonyms:5-Amino-6-chloroquinoline;6-chloroquinolin-5-amine;341010-40-0;MFCD02947117;5-Quinolinamine, 6-chloro-;6-Chloro-5-quinolinamine;SCHEMBL4508284;CHEMBL4860099;DTXSID60485177;MKJUMRMBGSXZBU-UHFFFAOYSA-N;BCP11502;AKOS006276352;SB67499;DS-10899;SY103081;AM20061667;CS-0019054;FT-0709242;EN300-6474368;A875103;Z1198161121;2-(2,3-NAPHTHALIMINO)ETHYLTRIFLUOROMETHANESULFONATE

Chemical Property of 5-Amino-6-chloroquinoline

Chemical Property:

• Refractive Index: 1.712
• Boiling Point: 331.135 °C at 760 mmHg
• PKA: 4.75±0.15(Predicted)
• Flash Point: 154.065 °C
• PSA: 38.91000
• Density: 1.363 g/cm³
• LogP: 3.05160
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• XLogP3: 1.8
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 178.0297759
• Heavy Atom Count: 12
• Complexity: 163

Purity/Quality:

98%min ^*data from raw suppliers

5-Amino-6-chloroquinoline ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC2=C(C=CC(=C2N)Cl)N=C1

Technology Process of 5-Amino-6-chloroquinoline

There total 6 articles about 5-Amino-6-chloroquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6‐chloro‐5‐nitroquinoline (86984-32-9) → 5-Amino-6-chlorchinolin (341010-40-0)

Guidance literature:

With hydrogenchloride; tin(ll) chloride;

Reference yield:

6-chloroquinoline (612-57-7) → 5-Amino-6-chlorchinolin (341010-40-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid monohydrate; fuming nitric acid

2: iodine; red phosphorus; water

With phosphorus; sulfuric acid; water; iodine; nitric acid;

Reference yield:

4-Chloro-3-nitroaniline (635-22-3) → 5-Amino-6-chlorchinolin (341010-40-0)

Guidance literature:

Multi-step reaction with 2 steps

1: concentrated sulfuric acid; picric acid

2: iodine; red phosphorus; water

With phosphorus; sulfuric acid; water; iodine; 2,4,6-Trinitrophenol;

upstream raw materials:

6‐chloro‐5‐nitroquinoline

water

iodine

hydrogenchloride

Downstream raw materials:

5,6-dichloro-quinoline

Refernces