(R)-(-)-3-phenylbutyric acid methyl ester

Base Information Edit

Chemical Name:(R)-(-)-3-phenylbutyric acid methyl ester
CAS No.:1441-20-9
Molecular Formula:C₁₁H₁₄O₂
Molecular Weight:178.231
Hs Code.:
Mol file:1441-20-9.mol

Synonyms:(R)-(-)-3-phenylbutyric acid methyl ester

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Chemical Property of (R)-(-)-3-phenylbutyric acid methyl ester Edit

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Technology Process of (R)-(-)-3-phenylbutyric acid methyl ester

There total 27 articles about (R)-(-)-3-phenylbutyric acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 186581-53-3,908094-01-9,334-88-3
diazomethane

: 4593-90-2,772-15-6
(S)-2-phenylbutanoic acid

: 1441-20-9
(R)-(-)-3-phenylbutyric acid methyl ester

Guidance literature:: In diethyl ether; at 20 ℃; for 2h;
DOI:10.1021/ja952835t

Reference yield: 95.0%

: methyl (E)-3-phenyl-2-butenoate

: 1441-20-9
(R)-(-)-3-phenylbutyric acid methyl ester

Guidance literature:: With aluminum (III) chloride; nickel(II) bromide dimethoxyethane; N,N-dimethyl-formamide; [2R-[1(2'R*,5'R*),2a,5b]]-1,1'-(1,2-phenylene)bis[2,5-dimethylphospholane]; In water; at 110 ℃; for 24h; Inert atmosphere; Glovebox; Schlenk technique;
DOI:10.1021/acs.orglett.6b02662