2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene

Base Information

• Chemical Name: 2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene
• CAS No.: 421554-39-4
• Molecular Formula: C₂₀H₁₀Br₄O₂
• Molecular Weight: 601.914
• Mol file: 421554-39-4.mol

Synonyms:2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene

Chemical Property of 2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene

There total 4 articles about 2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

1-bromo-4-(trimethylsilyl)benzene (6999-03-7) + 3,6-dibromo-2,5-phenylenedi(carboxylic acid chloride) (13815-90-2) → 2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene (421554-39-4)

Guidance literature:

With aluminium trichloride; In dichloromethane; at 0 - 20 ℃;

DOI:10.1002/1521-3765(20011203)7:23<5118::AID-CHEM5118>3.0.CO;2-1

Reference yield:

2,5-dibromoterephthalaldehyde (63525-48-4) → 2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene (421554-39-4)

Guidance literature:

Multi-step reaction with 3 steps

1: aq. KMnO₄

2: 100 percent / oxalyl chloride

3: 60 percent / aluminum chloride / CH₂Cl₂ / 0 - 20 °C

With potassium permanganate; aluminium trichloride; oxalyl dichloride; In dichloromethane; 3: Friedel-Crafts acylation;

DOI:10.1002/1521-3765(20011203)7:23<5118::AID-CHEM5118>3.0.CO;2-1

Reference yield:

2,5-dibromoterephtalic acid (13731-82-3) → 2.5-bis(p-bromobenzoyl)-1,4-dibromobenzene (421554-39-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 100 percent / oxalyl chloride

2: 60 percent / aluminum chloride / CH₂Cl₂ / 0 - 20 °C

With aluminium trichloride; oxalyl dichloride; In dichloromethane; 2: Friedel-Crafts acylation;

DOI:10.1002/1521-3765(20011203)7:23<5118::AID-CHEM5118>3.0.CO;2-1

upstream raw materials:

1-bromo-4-(trimethylsilyl)benzene

3,6-dibromo-2,5-phenylenedi(carboxylic acid chloride)

2,5-dibromoterephtalic acid

2,5-dibromo-p-xylene

Downstream raw materials:

2,5-bis(p-iodobenzyl)-1,4-diiodobenzene

Refernces